- ►endojournals.org A Merglen, S Theander, B Rubi, G Chaffard, … - Endocrinology, 2004 - Endocrine Soc Rat insulinoma-derived INS-1 cells constitute a widely used ß-cell surrogate.
However, due to their nonclonal nature, INS-1 cells are heterogeneous and are
not stable over extended culture periods. We have isolated clonal INS-1E ... Cited by 129 - Related articles - BL Direct - All 6 versions
- ►pubget.com [PDF] AA Toye, JD Lippiat, P Proks, K Shimomura, L … - Diabetologia, 2005 - Springer Page 1. Diabetologia (2005) 48: 675–686 DOI 10.1007/s00125-005-1680-z ARTICLE AA
Toye . JD Lippiat . P. Proks . K. Shimomura . L.Bentley . A. Hugill . ... Cited by 55 - Related articles - All 4 versions
- ►jbc.org B Rubi, A del Arco, C Bartley, J Satrustegui, … - Journal of Biological Chemistry, 2004 - ASBMB The NADH shuttle system, which transports reducing equivalents from the cytosol
to the mitochondria, is essential for the coupling of glucose metabolism to
insulin secretion in pancreatic beta cells. Aralar1 and citrin are two ... Cited by 28 - Related articles - All 6 versions
K Bender, P Newsholme, L Brennan, P … - Biochemical Society Transactions, 2006 - biochemsoctrans.org Introduction The significance of redox shuttle mechanisms has been extens- ively
described in brain, smooth muscle and cardiac tissue [1– 3]. However, recent
research has revealed their presence and importance to energy metabolism in ... Cited by 8 - Related articles - View as HTML - BL Direct - All 4 versions
- ►endojournals.org AJ Weinhaus, MT Tabiin, P Poronnik, CA … - Journal of Clinical Endocrinology & Metabolism, 2003 - Endocrine Soc Fetal pancreatic ß-cells release insulin poorly in response to glucose;
however, the cellular mechanism for this is unknown. By using fura-2 to measure
changes in the cytoplasmic free Ca 2+ concentration in ß-cells, we ... Cited by 7 - Related articles - BL Direct - All 4 versions
- ►oregonstate.edu [PDF] MJ MacDonald, FWR Chaplen, CK Triplett, Q … - Archives of Biochemistry and Biophysics, 2006 - Elsevier Glyceraldehyde (GA) has been used to study insulin secretion for decades and it
is widely assumed that β-cell metabolism of GA after its phosphorylation by
triokinase is similar to metabolism of glucose; that is metabolism through ... Cited by 5 - Related articles - All 8 versions
- ►physiology.org PO Westermark, JH Kotaleski, A Bjorklund, V … - American Journal of Physiology- Endocrinology And …, 2007 - Am Physiological Soc The pancreatic -cells respond to an increased glycolytic flux by secreting
insulin. The signal propagation goes via mitochondrial metabolism, which relays
the signal to different routes. One route is an increased ATP production ... Cited by 3 - Related articles - BL Direct - All 5 versions
A Zakrzewska, PO Schnell, JB Striet, A Hui, … - Journal of neurochemistry, 2005 - pubmedcentral.nih.gov Transcription co-activators and histone acetyltransferases, p300 and cyclic AMP
responsive element-binding protein-binding protein (CBP), participate in hypoxic
activation of hypoxia-inducible genes. Here, we show that exposure of PC12 ... Cited by 3 - Related articles - BL Direct - All 5 versions
- ►nutrition.org R Hageman, C Severijnen, BJM van de … - Journal of Nutrition, 2008 - Am Soc Nutrition Three studies were carried out to help define an optimal protein blend for use
in a nutritional product for diabetic patients. To this end, we tested the
effects of coinfusions of combinations of different types of carbohydrates ... Cited by 1 - Related articles - All 4 versions