- ►diabetesjournals.org I Cozar-Castellano, KK Takane, R Bottino, … - Diabetes, 2004 - Am Diabetes Assoc The major regulator of the gap-1/synthesis phase (G 1 /S) cell cycle checkpoint
is the retinoblastoma protein (pRb), and this is regulated in part by the
activities of cyclin-dependent kinase (cdk)-4 and the D cyclins. ... Cited by 57 - Related articles - BL Direct - All 4 versions
- ►jbc.org A Garcia-Ocana, KK Takane, VT Reddy, JC … - Journal of Biological Chemistry, 2003 - ASBMB Hepatocyte growth factor (HGF) increases beta cell proliferation and function in
rat insulin promoter (RIP)-targeted transgenic mice. RIP-HGF mouse islets also
function superiorly to normal islets in a transplant setting. Here, we ... Cited by 55 - Related articles - BL Direct - All 5 versions
- ►pnas.org T Okada, CW Liew, J Hu, C Hinault, MD Michael … - Proceedings of the National Academy of Sciences, 2007 - National Acad Sciences Insulin and insulin-like growth factor 1 (IGF1) are ubiquitous growth factors
that regulate proliferation in most mammalian tissues including pancreatic
islets. To explore the specificity of insulin receptors in compensatory ... Cited by 42 - Related articles - BL Direct - All 9 versions
- ►pnas.org S Chen, J Ding, R Bekeredjian, B Yang, RV … - Proceedings of the National Academy of Sciences, 2006 - National Acad Sciences This study describes a method of gene delivery to pancreatic islets of adult,
living animals by ultrasound targeted microbubble destruction (UTMD). The
technique involves incorporation of plasmids into the phospholipid shell of ... Cited by 37 - Related articles - BL Direct - All 9 versions
- ►diabetesjournals.org J Roccisana, V Reddy, RC Vasavada, JA … - Diabetes, 2005 - Am Diabetes Assoc Overexpression of hepatocyte growth factor (HGF) in the ß-cell of transgenic
mice enhances ß-cell proliferation, survival, and function. In the current
studies, we have used conditional ablation of the c-met gene to uncover the ... Cited by 31 - Related articles - All 6 versions
Y Fujinaka, D Sipula, A Garcia-Ocaña, RC … - Diabetes, 2004 - Am Diabetes Assoc Transgenic overexpression of either parathyroid hormone-related peptide (PTHrP)
or mouse placental lactogen type 1 (mPL1) in pancreatic β-cells, using the rat
insulin II promoter (RIP), results in islet hyperplasia either through ... Cited by 27 - Related articles - BL Direct - All 5 versions
S Del Prato, WJ Wishner, J Gromada, BJ … - Diabetes, Obesity and Metabolism, 2004 - diabetes.org.br Prospective studies have shown that insulin resistance (IR) and impaired insulin
secretion are independent pre- decessors and predictors of overt diabetes in
genetically predisposed individuals [1–3]. Studies involving sub- jects ... Cited by 24 - Related articles - View as HTML - BL Direct - All 6 versions
- ►asnjournals.org A Ortega, D Ramila, JA Ardura, V Esteban, M … - Journal of the American Society of Nephrology, 2006 - Am Soc Nephrol Parathyroid hormone–related protein (PTHrP) is shortly upregulated in acute
renal injury, but its pathophysiologic role is unclear. Investigated was whether
PTHrP might act as a profibrogenic factor in mice that do or do not ... Cited by 23 - Related articles - BL Direct - All 5 versions
ES Fenjves, MS Ochoa, C Gay-Rabinstein, RD … - Transplantation, 2004 - journals.lww.com Background. The transfer of cytoprotective genes to isolated pancreatic islets
may contribute to their en- hanced survival in the transplant setting. Our
labora- tory established the expression of functional erythro- poietin ... Cited by 22 - Related articles - BL Direct - All 3 versions
- ►physiology.org RH Hastings, F Araiza, DW Burton, L Zhang, M … - American Journal of Physiology- Cell Physiology, 2003 - Am Physiological Soc Parathyroid hormone-related protein (PTHrP) is expressed in more advanced,
aggressive tumors and may play an active role in cancer progression. This study
investigated the effects of PTHrP on apoptosis after UV irradiation, Fas ... Cited by 19 - Related articles - BL Direct - All 4 versions
