R Belfort, SA Harrison, K Brown, C Darland, J … - New England Journal …, 2006 - content.nejm.org Methods We randomly assigned 55 patients with impaired glucose tolerance or type 2 diabetes and
liver biopsy–confirmed nonalcoholic steatohepatitis to 6 months of treatment with a hypocaloric
diet (a reduction of 500 kcal per ... Cited by 386 - Related articles - BL Direct - All 7 versions
E Bugianesi, AJ McCullough, G Marchesini… - Hepatology, 2005 - interscience.wiley.com Insulin resistance (IR) is the pathophysiological hallmark of nonalcoholic fatty liver disease
(NAFLD), one of the most common causes of chronic liver disease in Western countries. We review the
definition of IR, the methods for ... Cited by 170 - Related articles - BL Direct - All 3 versions
- ►fasebj.org [PDF] A Bonen, ML Parolin, GR Steinberg, J Calles- … - The FASEB Journal, 2004 - FASEB Page 1. The FASEB Journal express article 10.1096/fj.03-1065fje. Published online May 7, 2004.
Triacylglycerol accumulation in human obesity and type 2 diabetes is associated with increased rates
of skeletal muscle fatty acid transport and increased sarcolemmal FAT/CD36 ... Cited by 132 - Related articles - BL Direct - All 7 versions
- ►bmj.com EL Thomas, G Hamilton, N Patel, R O'dwyer, CJ … - British Medical …, 2005 - gut.bmj.com Results: IHCL signals were detectable in all subjects but were significantly greater in hepatic
steatosis (geometric mean (GM) 11.5 (interquartile range (IQR) 7.0–39.0)) than in normal
volunteers (GM 2.7 (IQR 0.7–9.3); ... Cited by 113 - Related articles - BL Direct - All 16 versions
M Roden - Nature Reviews Endocrinology, 2006 - nature.com Hepatic steatosis is defined by an increased content of hepatocellular lipids (HCLs) and is
frequently observed in insulin-resistant states including type 2 diabetes mellitus. A dietary excess
of saturated fat contributes ... Cited by 73 - Related articles - BL Direct - All 4 versions
- ►diabetesjournals.org C Anderwald, G Brabant, E Bernroider, R Horn, A … - Diabetes, 2003 - Am Diabetes Assoc The gastric peptide ghrelin augments and the adipocyte-derived hormone leptin reduces appetite and
food intake. In the central nervous system, insulin directly decreases hunger sensation but could
also act indirectly by modulating ... Cited by 62 - Related articles - BL Direct - All 4 versions
- ►physiology.org R Barazzoni, A Bosutti, M Stebel, MR … - American Journal of …, 2005 - Am Physiological Soc Ghrelin is a gastric hormone increased during caloric restriction and fat depletion. A role of
ghrelin in the regulation of lipid and energy metabolism is suggested by fat gain independent of
changes in food intake during ... Cited by 62 - Related articles - All 3 versions
- ►diabetesjournals.org M Krssak, A Brehm, E Bernroider, C Anderwald, P … - Diabetes, 2004 - Am Diabetes Assoc Decreased skeletal muscle glucose disposal and increased endogenous glucose production (EGP)
contribute to postprandial hyperglycemia in type 2 diabetes, but the contribution of hepatic
glycogen metabolism remains ... Cited by 56 - Related articles - BL Direct - All 4 versions
- ►ahajournals.org [PDF] JM McGavock, I Lingvay, I Zib, T Tillery, N Salas, R … - Circulation, 2007 - Am Heart Assoc Kluwer Health, 351 West Camden Street, Baltimore, MD 21202-2436. Phone: 410-528-4050. Permissions:
Permissions & Rights Desk, Lippincott Williams & Wilkins, a division of Wolters ... A 1 H-Magnetic
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M Roden, E Bernroider - Best Practice & Research Clinical Endocrinology & …, 2003 - Elsevier The liver is mainly responsible for maintaining normal concentrations of blood glucose by its
ability to store glucose as glycogen and to produce glucose from glycogen breakdown or gluconeogenic
precursors. During the last decade, ... Cited by 48 - Related articles - All 3 versions