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Scholar Results 1 - 10 of about 24 citing Zagon: Naltrexone, an opioid antagonist, facilitates reepithelialization of the cornea in.... (0.15 sec) 

Insulin, not leptin, promotes in vitro cell migration to heal monolayer wounds in human …

- iovs.org
LJ Shanley, CD McCaig, JV Forrester, M Zhao - Investigative ophthalmology & visual science, 2004 - ARVO
METHODS. Scratch wounds were created in monolayers of an immortalized human
corneal epithelial cell (HCEC) line. The wounded monolayers were exposed to
insulin and leptin. Wound areas were measured every hour after wounding for ...
Cited by 23 - Related articles - BL Direct - All 6 versions

Particle-mediated gene transfer of opioid growth factor receptor cDNA regulates cell …


IS Zagon, JW Sassani, MF Verderame, PJ … - Cornea, 2005 - journals.lww.com
Cornea. Wolters Kluwer Health Logo. All Issues. ...
Cited by 14 - Related articles - BL Direct - All 3 versions

[PDF] Low-dose naltrexone therapy improves active Crohn's disease


JP Smith, H Stock, S Bingaman, D Mauger, M … - American Journal of Gastroenterology, 2007 - fertilitycare.net
METHODS: Eligible subjects with histologically and endoscopically confirmed
active Crohn's disease activity index (CDAI) score of 220–450 were enrolled in
a study using 4.5 mg naltrexone/day. Infliximab was not allowed for a ...
Cited by 11 - Related articles - View as HTML - BL Direct - All 6 versions

Deletion of delta-opioid receptor in mice alters skin differentiation and delays wound healing


M Bigliardi-Qi, C Gaveriaux-Ruff, H Zhou, C Hell … - Differentiation, 2006 - interscience.wiley.com
Abstract In addition to their well-known antinociceptive action, opioids can
modulate non-neuronal functions, such as immune activity and physiology of
different cell types. Several findings suggest that the δ-opioid receptor ...
Cited by 12 - Related articles - BL Direct - All 3 versions

Insulin treatment ameliorates impaired corneal reepithelialization in diabetic rats

- diabetesjournals.org
IS Zagon, JW Sassani, PJ McLaughlin - Diabetes, 2006 - Am Diabetes Assoc
Patients with diabetes are at an increased risk for developing corneal
disorders, often as a result of surgical and nonsurgical trauma. This study
investigated whether intensive treatment of diabetes with the goal of ...
Cited by 13 - Related articles - BL Direct - All 5 versions

Regulation of corneal repair by particle-mediated gene transfer of opioid growth factor …


IS Zagon, JW Sassani, KJ Malefyt, PJ … - Archives of Ophthalmology, 2006 - Am Med Assoc
Results Eyes transfected with sense constructs of OGFr had corneal defects that
were 24%, 52%, and 50% larger than the EV group at 16, 24, and 28 hours,
respectively. Conversely, corneas transfected with antisense constructs of ...
Cited by 10 - Related articles - BL Direct - All 4 versions

Use of topical insulin to normalize corneal epithelial healing in diabetes mellitus

- biozol.de [PDF] 
IS Zagon, MS Klocek, JW Sassani, PJ … - Archives of Ophthalmology, 2007 - archopht.highwire.org
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Cited by 11 - Related articles - BL Direct - All 8 versions

Topically applied naltrexone restores corneal reepithelialization in diabetic rats


MS Klocek, JW Sassani, PJ McLaughlin, IS … - Journal of Ocular Pharmacology and Therapeutics, 2007 - liebertonline.com
MATTHEW S. KLOCEK, 1 JOSEPH W. SASSANI, 2 ... PATRICIA J. M C LAUGHLIN, 1 and
IAN S. ZAGON 1 ... Purpose: Complications of diabetes include an increased risk
of delayed corneal epithelial wound healing. This study examined the ...
Cited by 10 - Related articles - BL Direct - All 4 versions

Corneal safety of topically applied naltrexone


IS Zagon, MS Klocek, JW Sassani, DT Mauger … - Journal of Ocular Pharmacology & Therapeutics, 2006 - liebertonline.com
IAN S. ZAGON, 1 MATTHEW S. KLOCEK, 1 JOSEPH W. SASSANI, 2 DAVID T. MAUGER, 3
... Purpose: Naltrexone (NTX), an opioid antagonist, accelerates wound healing
of corneal ep- ithelium in normal and diabetic animals. This study examined ...
Cited by 8 - Related articles - BL Direct - All 5 versions

Naltrexone accelerates healing without compromise of adhesion complexes in normal and …


IS Zagon, JW Sassani, RL Myers, PJ … - Brain research bulletin, 2007 - Elsevier
Naltrexone (NTX) is an opioid antagonist that accelerates wound healing of
corneal epithelium in normal and diabetic animals. Junctional complexes
(hemidesmosomes) are important in establishing adhesion of the corneal ...
Cited by 6 - Related articles - All 4 versions


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