- ►ahajournals.org N Marx, J Froehlich, L Siam, J Ittner, G Wierse, … - … , and Vascular Biology, 2003 - Am Heart Assoc Background— Matrix metalloproteinases (MMPs) are critically involved in the development of
unstable plaques. Although arteriosclerotic lesions in patients with diabetes mellitus are more
unstable than those of nondiabetic subjects, nothing is known about serum levels of ... Cited by 228 - Related articles - BL Direct - All 7 versions
- ►ahajournals.org AR Brady, SG Thompson, FGR Fowkes, RM … - Circulation, 2004 - Am Heart Assoc Methods and Results— In this study, 1743 patients were monitored for changes in AAA diameter
by ultrasonography over a mean follow-up of 1.9 years. Mean initial AAA diameter and growth
rate were 43 mm (range 28 to 85 mm) and 2.6 mm/year (95% range, –1.0 to 6.1 mm/year), ... Cited by 141 - Related articles - BL Direct - All 6 versions
- ►physiology.org JC Frisbee - American Journal of Physiology- Heart and …, 2003 - Am Physiological Soc Whereas previous studies have demonstrated that the development of syndrome X in obese
Zucker rats (OZR) is associated with impaired arteriolar reactivity to vasoactive stimuli, additional
results from these studies indicate that the passive diameter of skeletal muscle arterioles ... Cited by 38 - Related articles - BL Direct - All 5 versions
A Ergul, V Portik-Dobos, AD … - AJP-Heart and …, 2003 - ajpheart.physiology.org.p. … Degradation of the extracellular matrix proteins by matrix metalloproteinases (MMP) is an important
regulatory step in the vascular remodeling process. Recent studies demonstrated that ET A receptors
regulate cardiac MMP activity and fibrosis in DOCA-salt hypertension. However, little is ... Cited by 35 - Related articles - BL Direct - All 5 versions
- ►ahajournals.org AWY Chung, YN Hsiang, LA Matzke, BM McManus … - Circulation …, 2006 - Am Heart Assoc Impaired angiogenesis could contribute to the increased incidence of coronary and peripheral
artery disease in diabetic patients. Angiogenesis is initiated by vascular endothelial growth factor
(VEGF), a potent angiogenic cytokine, and suppressed by angiostatin, which is generated ... Cited by 40 - Related articles - All 8 versions
- ►ahajournals.org S Jesmin, I Sakuma, Y Hattori, A … - … , thrombosis, and vascular …, 2003 - Am Heart Assoc Methods and Results— By immunohistochemistry and in situ hybridization, transforming growth
factor-ß 1 (TGF-ß 1 ) expression increased in coronary vessels, the perivascular area, and cardiomyocytes
in diabetic rat hearts. Increased expression of plasminogen activator inhibitor-1 (PAI-1) in ... Cited by 33 - Related articles - BL Direct - All 8 versions
NP Kadoglou, SS Daskalopoulou, D Perrea, CD Liapis - Angiology, 2005 - ang.sagepub.com Diabetes mellitus (DM) is associated with an increased incidence of cardiovascular events and
microvascular complications. These complications contribute to the morbidity and mortality associated
with DM. There is increasing evidence supporting a role for matrix metallopro- teinases ( ... Cited by 31 - Related articles - All 3 versions
G Kesava Reddy - Microvascular Research, 2004 - Elsevier Diabetes mellitus is major risk factor for cardiovascular disease, and atherosclerosis accounts
for most of the morbidity and mortality of diabetic patients. To examine the effects of diabetes
on the vessel wall, we examined the association of collagen cross-linking in relation to ... Cited by 26 - Related articles - All 4 versions
- ►diabetesjournals.org MH Tayebjee, H Lim, RJ MacFadyen, GYH Lip - Diabetes Care, 2004 - Am Diabetes Assoc Sixty-five of the recruited diabetic patients (of whom 36 had cardiovascular disease) consented
to intensified diabetes and cardiovascular risk management therapy. This consisted of 3 monthly
consultations, lifestyle advice, and adjusting oral hypoglycemia therapy to achieve HbA ... Cited by 26 - Related articles - BL Direct - All 5 versions
SW Lee, KE Song, DS Shin, SM Ahn, ES Ha, DJ … - Diabetes research and …, 2005 - Elsevier In vivo and in vitro experimental findings indicate that the hyperglycemic diabetic milieu can induce
altered expression of the matrix metalloproteinase (MMP) genes and contribute to imbalances
in vascular matrix homeostasis. We examined the plasma levels of enzymes and ... Cited by 26 - Related articles - All 7 versions