- ►diabetesjournals.org G Wolf, S Chen, FN Ziyadeh - Diabetes, 2005 - Am Diabetes Assoc Nephropathy is a major complication of diabetes. Alterations of mesangial cells have traditionally
been the focus of research in deciphering molecular mechanisms of diabetic nephropathy. Injury of
podocytes, if recognized at all, ... Cited by 188 - Related articles - All 9 versions
BF Schrijvers, A Flyvbjerg, AS De Vriese - Kidney international, 2004 - nature.com Received 24 April 2003; Revised 7 August 2003; Re-revised 25 September 2003; Accepted 3 December
2003. ... The role of vascular endothelial growth factor (VEGF) in renal pathophysiology. Vascular
endothelial growth factor (VEGF) is ... Cited by 145 - Related articles - BL Direct - All 7 versions
EC Tsilibary - The Journal of Pathology, 2003 - ingentaconnect.com The alterations in the microvascular system of diabetes mellitus patients are responsible for the
most devastating complications of this widespread disease. In the kidney, the microan- giopathy
leads to thickening of the ... Cited by 129 - Related articles - BL Direct - All 7 versions
- ►endojournals.org BF Schrijvers, AS De Vriese, A Flyvbjerg - Endocrine reviews, 2004 - Endocrine Soc At present, diabetic kidney disease affects about 15–25% of type 1 and 30–40% of type 2 diabetic
patients. Several decades of extensive research has elucidated various pathways to be implicated in
the development of diabetic kidney ... Cited by 122 - Related articles - All 5 versions
- ►diabetesjournals.org Y Yamamoto, Y Maeshima, H Kitayama, S Kitamura, Y … - Diabetes, 2004 - Am Diabetes Assoc In the early stage of diabetic nephropathy (one of the major microvascular complications of
diabetes) glomerular hyperfiltration and hypertrophy are observed. It is clinically important to
regulate glomerular hypertrophy for ... Cited by 84 - Related articles - BL Direct - All 6 versions
- ►ahajournals.org WC Aird - Circulation research, 2007 - Am Heart Assoc Endothelial cells, which form the inner cellular lining of blood vessels and lymphatics, display
remarkable heterogeneity in structure and function. This is the second of a 2-part review on the
phenotypic heterogeneity of blood ... Cited by 82 - Related articles - All 12 versions
- ►diabetesjournals.org D Ray, M Mishra, S Ralph, I Read, R Davies, P … - Diabetes, 2004 - Am Diabetes Assoc Diabetic retinopathy and nephropathy cause significant morbidity in patients with diabetes. Vascular
endothelial growth factor (VEGF) is a potent angiogenic and vascular permeability factor and is
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P Dasgupta - Pharmacology and Therapeutics, 2004 - Elsevier Angiogenesis, the development of new blood vessels is a crucial process both for tumor growth and
metastatic dissemination. Additionally, dysregulation in angiogenesis has been implicated in the
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A Flyvbjerg, L Denner, BF Schrijvers, RG Tilton, TH … - Diabetes, 2004 - Am Diabetes Assoc Advanced glycation end products (AGEs) have been implicated in the pathogenesis of diabetic kidney
disease. The actions of AGEs are mediated both through a non–receptor-mediated pathway and through
specific receptors for AGE (RAGEs). ... Cited by 68 - Related articles - BL Direct - All 4 versions
ML Caramori, M Mauer - Current opinion in nephrology and …, 2003 - journals.lww.com Recent findings: There have been advances in the understanding of diabetic nephropathy pathology.
Clearly, structural changes may be advanced before any clinical findings are apparent. Not all
functional consequences of the ... Cited by 68 - Related articles - BL Direct - All 7 versions