B Nikolic, Y Takeuchi, I Leykin, Y Fudaba, RN … - Diabetes, 2004 - Am Diabetes Assoc Bone marrow transplantation from diabetes-resistant strains with complete
replacement of the recipient immune system by the allogeneic donor has led to
tolerance to donor islets and cure of diabetes in a mouse model of type 1 ... Cited by 56 - Related articles - BL Direct - All 4 versions
- ►jimmunol.org A Yamada, AD Salama, M Sho, N Najafian, T … - The Journal of Immunology, 2005 - Am Assoc Immnol The inability to reproducibly induce robust and durable transplant tolerance
using CD28-B7 pathway blockade is in part related to the persistence of
alloreactive effector/memory CD8 + T cells that are less dependent on this ... Cited by 54 - Related articles - All 5 versions
- ►jimmunol.org R Abdi, TK Means, T Ito, RN Smith, N Najafian … - The Journal of Immunology, 2004 - Am Assoc Immnol Chemokines have a pivotal role in the mobilization and activation of specific
leukocyte subsets in acute allograft rejection. However, the role of specific
chemokines and chemokine receptors in islet allograft rejection has not ... Cited by 43 - Related articles - BL Direct - All 4 versions
- ►jimmunol.org AD Salama, KL Womer, MH Sayegh - The Journal of Immunology, 2007 - Am Assoc Immnol Modern immunosuppressive regimens for organ transplantation have resulted in
excellent short-term results but less dramatic improvements in long-term
outcomes. Moreover, they are associated with significant deleterious ... Cited by 39 - Related articles - All 5 versions
L Makhlouf, ST Grey, V Dong, E Csizmadia, … - Transplantation, 2004 - journals.lww.com Background. The authors' laboratory previously demonstrated that long-term
tolerance to class I-dis- parate renal allografts in miniature swine can be in-
duced by a short course of cyclosporine A (CsA), and that this stable ... Cited by 37 - Related articles - BL Direct - All 4 versions
- ►rupress.org ML Ford, BH Koehn, ME Wagener, W Jiang, S … - Journal of Experimental Medicine, 2007 - jem.rupress.org After a brief period of antigenic stimulation, T cells become committed to a
program of autonomous expansion and differentiation. We investigated the role of
antigen-specific T cell precursor frequency as a possible cell-extrinsic ... Cited by 36 - Related articles - BL Direct - All 7 versions
AW Bingaman, DL Farber - American Journal of Transplantation, 2004 - interscience.wiley.com The adaptive immune system is endowed with long-lived memory to recall previous
antigen encounters and respond more effectively to them. Memory immune responses
are mediated by antigen-specific memory T lymphocytes that exhibit enhanced ... Cited by 34 - Related articles - BL Direct - All 5 versions
- ►jimmunol.org MD Vu, F Amanullah, Y Li, G Demirci, MH … - The Journal of Immunology, 2004 - Am Assoc Immnol Costimulatory signals and growth factor signals play a key role in commanding T
cell activation and T cell effector function. However, how costimulatory signals
and growth factor signals interact and integrate into the activation ... Cited by 32 - Related articles - BL Direct - All 4 versions
- ►ualberta.ca [PDF] AN Balamurugan, R Bottino, N Giannoukakis … - Pancreas, 2006 - journals.lww.com Abstract: Pancreatic islet cell transplantation is an attractive treatment of
type 1 diabetes (T1D). The success enhanced by the Edmonton protocol has
fostered phenomenal progress in the field of clinical islet transplantation ... Cited by 31 - Related articles - BL Direct - All 4 versions
- ►jimmunol.org TM Kupfer, ML Crawford, K Pham, RG Gill - The Journal of Immunology, 2005 - Am Assoc Immnol When transplanted into type 1a diabetic recipients, islet allografts are subject
both to conventional allograft immunity and, presumably, to recurrent autoimmune
(islet-specific) pathogenesis. Importantly, CD4 T cells play a central role ... Cited by 21 - Related articles - All 4 versions