G Mellitzer, S Bonné, RF Luco, M Van De … - The EMBO …, 2006 - pubmedcentral.nih.gov Neurogenin 3 (Ngn3) is key for endocrine cell specification in the embryonic pancreas and induction
of a neuroendocrine cell differentiation program by misexpression in adult pancreatic duct
cells. We identify the gene encoding IA1, a zinc-finger transcription factor, as a direct ... Cited by 58 - Related articles - BL Direct - All 7 versions
- ►endojournals.org JP Chanoine, ACK Wong - Endocrinology, 2004 - Endocrine Soc Ghrelin is an orexigenic peptide secreted mainly by the stomach in adult rats. Ghrelin concentrations
increase with fasting and decrease after food intake. Ghrelin is also present in the placenta and
in the fetal stomach, but the role of fetal ghrelin remains unclear. In this study, we ... Cited by 53 - Related articles - BL Direct - All 5 versions
- ►physiology.org M Dufresne, C Seva, D Fourmy - Physiological reviews, 2006 - Am Physiological Soc Cholecystokinin and gastrin receptors (CCK1R and CCK2R) are G protein-coupled receptors
that have been the subject of intensive research in the last 10 years with corresponding advances
in the understanding of their functioning and physiology. In this review, we first describe ... Cited by 51 - Related articles - BL Direct - All 5 versions
- ►endocrinology-journals.org AM Ackermann, M Gannon - Journal of molecular endocrinology, 2007 - Soc Endocrinology Pancreatic ß-cells are responsible for producing all of the insulin required by an organism to
maintain glucose homeostasis. Defects in development, maintenance, or expansion of ß-cell
mass can result in impaired glucose metabolism and diabetes. Thus, identifying the ... Cited by 37 - Related articles - All 4 versions
M Fukushima, H Suzuki, Y Seino - Diabetes research and clinical practice, 2004 - Elsevier We have examined the contribution of insulin secretion and insulin resistance to glucose intolerance
in Japanese. Some indices of insulin secretion and insulin sensitivity based on the results of
OGTT were used. The decline of insulin secretion capacity was significant throughout the ... Cited by 35 - Related articles - All 3 versions
- ►endojournals.org M Vincent, Y Guz, M Rozenberg, G Webb, M Furuta, D … - Endocrinology, 2003 - Endocrine Soc To date, the role of pancreatic hormones in pancreatic islet growth and differentiation is poorly
understood. To address this issue, we examined mice with a disruption in the gene encoding
prohormone convertase 2 (PC2). These mice are unable to process proglucagon, ... Cited by 25 - Related articles - BL Direct - All 4 versions
- ►endojournals.org PM Vuguin, MH Kedees, L Cui, Y Guz, RW Gelling, M … - Endocrinology, 2006 - Endocrine Soc Although glucagon (GLU) plays a pivotal role in glucose homeostasis, its role in the regulation
of fetal growth and maturation is poorly understood. These issues were examined in a line of
mice with a global deletion of the GLU receptor (Gcgr –/– ), which are characterized by ... Cited by 14 - Related articles - BL Direct - All 4 versions
L Wilding, M Gannon - Diabetes/Metabolism Reviews - interscience.wiley.com Ex vivo expansion of embryonic stem cells (ES cells) or pancreatic stem cells for insulin delivery
to diabetic patients provides potential for the restoration of islet function in these individuals.
Understanding the spatial and temporal requirements of crucial factors for endocrine ... Cited by 12 - Related articles - BL Direct - All 4 versions
A Rolletschek, G Kania, AM Wobus - Diabetologia, 2006 - Springer Page 1. FOR DEBATE Generation of pancreatic insulin-producing cells from embryonic
stem cells — 'Proof of principle', but questions still unanswered A. Rolletschek & G.
Kania & AM Wobus Received: 11 November 2005 /Accepted ... Cited by 11 - Related articles - All 3 versions
KH Yew, KL Prasadan, BL Preuett, MJ Hembree, CR … - Diabetes, 2004 - Am Diabetes Assoc The differentiation of pancreatic exocrine AR42J cells into insulin-expressing endocrine cells
has served as an important model for both endogenous in vivo β-cell differentiation as well as
potential application to β-cell engineering of progenitor cells. Exogenous activin, possibly ... Cited by 11 - Related articles - BL Direct - All 4 versions
