F Wuytack, L Raeymaekers, L Missiaen - Cell Calcium, 2002 - Elsevier Intracellular Ca 2+ -transport ATPases exert a pivotal role in the endoplasmic
reticulum and in the compartments of the cellular secretory pathway by
maintaining a sufficiently high lumenal Ca 2+ (and Mn 2+ ) concentration in ... Cited by 122 - Related articles - BL Direct - All 4 versions
- ►shouxi.net AK Cardozo, F Ortis, J Storling, YM Feng, J … - Diabetes, 2005 - Am Diabetes Assoc Cytokines and free radicals are mediators of β-cell death in type 1 diabetes.
Under in vitro conditions, interleukin-1β (IL-1β) + γ-interferon (IFN-γ)
induce nitric oxide (NO) production and apoptosis in rodent and human ... Cited by 102 - Related articles - All 8 versions
- ►diabetesjournals.org RN Kulkarni, MG Roper, G Dahlgren, DQ Shih, … - Diabetes, 2004 - Am Diabetes Assoc Mice with deletion of insulin receptor substrate (IRS)-1 (IRS-1 knockout [KO]
mice) show mild insulin resistance and defective glucose-stimulated insulin
secretion and reduced insulin synthesis. To further define the role of ... Cited by 66 - Related articles - BL Direct - All 4 versions
D Arnette, TB Gibson, MC Lawrence, B … - Journal of Biological Chemistry, 2003 - ASBMB We showed previously that ERK1/2 were activated by glucose and amino acids in
pancreatic cells. Here we examine and compare signaling events that are
necessary for ERK1/2 activation by glucose and other stimuli in cells. We ... Cited by 45 - Related articles - BL Direct - All 5 versions
KJ Mitchell, T Tsuboi, GA Rutter - Diabetes, 2004 - Am Diabetes Assoc Changes in intracellular Ca 2+ concentration play a key role in the regulation
of insulin secretion by glucose and other secretagogues. Here, we explore the
importance of the secretory pathway Ca 2+ -ATPase, plasma membrane-related ... Cited by 42 - Related articles - BL Direct - All 4 versions
- ►psu.edu [PDF] R Bertram, A Sherman - Bulletin of mathematical biology, 2004 - Springer Insulin-secreting β-cells, located within the pancreatic islets of Langerhans,
are excitable cells that produce regular bursts of action potentials when
stimulated by glucose. This system has been the focus of mathematical ... Cited by 34 - Related articles - All 6 versions
O Dyachok, E Gylfe - Journal of Biological Chemistry, 2004 - ASBMB Hormones, such as glucagon and glucagon-like peptide-1, potently amplify
nutrient stimulated insulin secretion by raising cAMP. We have studied how cAMP
affects Ca 2+ -induced Ca 2+ release (CICR) in pancreatic β-cells from ... Cited by 32 - Related articles - BL Direct - All 4 versions
GE Shull, G Okunade, LH Liu, P Kozel, M … - Ann NY Acad Sci, 2003 - interscience.wiley.com Abstract: It is known that plasma membrane Ca 2+ -transporting ATPases (PMCAs)
extrude Ca 2+ from the cell and that sarco(endo)plasmic reticulum Ca 2+ -ATPases
(SERCAs) and secretory pathway Ca 2+ -ATPases (SPCAs) sequester Ca 2+ in ... Cited by 32 - Related articles - BL Direct - All 4 versions
- ►physiology.org MZ Khaldi, Y Guiot, P Gilon, JC Henquin, JC … - American Journal of Physiology- Endocrinology And …, 2004 - Am Physiological Soc Chronic hyperglycemia has been shown to induce either a lack of response or an
increased sensitivity to glucose in pancreatic -cells. We reinvestigated this
controversial issue in a single experimental model by culturing rat islets ... Cited by 29 - Related articles - BL Direct - All 5 versions
- ►ahajournals.org JN Tsoporis, A Marks, A Haddad, F Dawood, … - Circulation, 2005 - Am Heart Assoc Methods and Results— We compared 21 wild-type (WT), 20 TG, and 24 KO mice over
35 days after experimental myocardial infarction with sham-operated controls
(n=56). Of those, 4 WT-infarcted mice, 7 TG-infarcted mice, and 1 ... Cited by 26 - Related articles - All 9 versions
