R Zimmermann, JG Strauss, G Haemmerle, G … - Science, 2004 - sciencemag.org Page 1. DOI: 10.1126/science.1100747 , 1383 (2004); 306 Science et al. Robert Zimmermann,
Adipose Triglyceride Lipase Fat Mobilization in Adipose Tissue Is Promoted by
www.sciencemag.org (this information is current as of May 12, 2009 ): The ... Cited by 345 - Related articles - All 6 versions
- ►portlandpress.com C Holm, T Østerlund, H Laurell, JA … - Annual review of nutrition, 2000 - Annual Reviews ▪ Abstract Hormone-sensitive lipase, the rate-limiting enzyme of intracellular TG hydrolysis, is a
major determinant of fatty acid mobilization in adipose tissue as well as other tissues. It plays a
pivotal role in lipid metabolism, ... Cited by 328 - Related articles - BL Direct - All 15 versions
CM Jenkins, DJ Mancuso, W Yan, HF Sims, B … - Journal of Biological …, 2004 - ASBMB Genetic knockout of hormone-sensitive lipase in mice has implicated the presence of other
intracellular triacylglycerol (TAG) lipases mediating TAG hydrolysis in adipocytes. Despite intense
interest in these TAG lipases, ... Cited by 219 - Related articles - BL Direct - All 5 versions
SJ Yeaman - Biochemical Journal, 2004 - pubmedcentral.nih.gov Although described initially as an intracellular adipocyte-specific triacylglycerol lipase, it is
now clear that HSL (hormone-sensitive lipase) is expressed in multiple tissues and plays a number of
roles in lipid metabolism, ... Cited by 99 - Related articles - BL Direct - All 8 versions
- ►diabetesjournals.org AW Cohen, B Razani, W Schubert, TM Williams, XB … - Diabetes, 2004 - Am Diabetes Assoc Recently, it was shown that caveolin-1 can be redirected from the cell surface to intracellular
lipid droplets in a variety of cell types. Here, we directly address the role of caveolin-1 in lipid
droplet formation and breakdown, ... Cited by 92 - Related articles - BL Direct - All 5 versions
- ►jbc.org H Ruan, HJ Pownall, HF Lodish - Journal of Biological Chemistry, 2003 - ASBMB Troglitazone (TGZ), a member of the thiazolidinedione class of anti-diabetic compounds and a
peroxisome proliferator activator receptor- (PPAR- ) agonist, restores systemic insulin sensitivity
and improves the full insulin ... Cited by 86 - Related articles - BL Direct - All 6 versions
- ►diabetesjournals.org EE Kershaw, JK Hamm, LAW Verhagen, O Peroni, M … - Diabetes, 2006 - Am Diabetes Assoc Adipose triglyceride lipase (ATGL) is a recently described adipose-enriched protein with
triglyceride-specific lipase activity. ATGL shares the greatest sequence homology with adiponutrin,
a nutritionally regulated protein ... Cited by 77 - Related articles - BL Direct - All 6 versions
KG Soni, R Lehner, P Metalnikov, P O'Donnell, M … - Journal of Biological …, 2004 - ASBMB Hydrolysis of triglycerides is central to energy homeostasis in white adipose tissue (WAT).
Hormone-sensitive lipase (HSL) was previously felt to mediate all lipolysis in WAT. Surprisingly,
HSL-deficient mice show active HSL- ... Cited by 71 - Related articles - BL Direct - All 5 versions
HH Zhang, SC Souza, KV Muliro, FB Kraemer, MS … - Journal of Biological …, 2003 - ASBMB Perilipin (Peri) A is a lipid droplet-associated phosphoprotein that acts dually as a suppressor of
basal (constitutive) lipolysis and as an enhancer of cyclic AMP-dependent protein kinase
(PKA)-stimulated lipolysis by both ... Cited by 71 - Related articles - BL Direct - All 6 versions
S Grönke, A Mildner, S Fellert, N Tennagels, S Petry, G … - Cell Metabolism, 2005 - Elsevier Energy homeostasis, a fundamental property of all organisms, depends on the ability to control the
storage and mobilization of fat, mainly triacylglycerols (TAG), in special organs such as mammalian
adipose tissue or the fat body of ... Cited by 68 - Related articles - All 13 versions
