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Scholar Results 1 - 10 of about 45 citing Sainsbury: Y2 receptor deletion attenuates the type 2 diabetic syndrome of ob/ob mice. (0.09 sec) 

[PDF] Neuropeptide Y acts directly in the periphery on fat tissue and mediates stress-induced …


LE Kuo, JB Kitlinska, JU Tilan, L Li, SB … - Nature medicine, 2007 - basicmed.med.ncku.edu.tw
The relationship between stress and obesity remains elusive. In response to
stress, some people lose weight, whereas others gain. Here we report that stress
exaggerates diet-induced obesity through a peripheral mechanism in the ...
Cited by 89 - Related articles - View as HTML - BL Direct - All 12 versions

NPY and Y receptors: lessons from transgenic and knockout models


S Lin, D Boey, H Herzog - Neuropeptides, 2004 - Elsevier
Neuropeptide Y (NPY) in the central nervous system is a major regulator of food
consumption and energy homeostasis. It also regulates blood pressure, induces
anxiolysis, enhances memory retention, affects circadian rhythms and ...
Cited by 62 - Related articles - All 10 versions

Endocannabinoids and the regulation of body fat: the smoke is clearing

- nih.gov [PDF] 
TL Horvath - Journal of Clinical Investigation, 2003 - Am Soc Clin Investig
Chronically elevated energy expenditure without a corresponding increase in
energy intake leads to wasting and death. Almost all species in the wild, and
the great majority of the human race, struggle with such negative energy ...
Cited by 50 - Related articles - BL Direct - All 8 versions

Synergistic effects of Y2 and Y4 receptors on adiposity and bone mass revealed in double …

- nih.gov
A Sainsbury, PA Baldock, C Schwarzer, N … - Molecular and Cellular Biology, 2003 - Am Soc Microbiol
Neuropeptide Y regulates numerous physiological processes via at least five
different Y receptors, but the specific roles of each receptor are still
unclear. We previously demonstrated that Y2 receptor knockout results in a ...
Cited by 47 - Related articles - BL Direct - All 4 versions

Development and application of rodent models for type 2 diabetes


D Chen, MW Wang - Diabetes Obesity and Metabolism, 2005 - interscience.wiley.com
The increasing worldwide incidence of diabetes in adults constitutes a global
public health burden. It is predicted that by 2025, India, China and the United
States will have the largest number of people with diabetes [1]. According ...
Cited by 43 - Related articles - All 4 versions

Absence of hormone-sensitive lipase inhibits obesity and adipogenesis in Lepob/ob mice

- jbc.org
M Sekiya, J Osuga, H Okazaki, N Yahagi, K … - Journal of Biological Chemistry, 2004 - ASBMB
Hormone-sensitive lipase (HSL) plays a crucial role in the hydrolysis of
triacylglycerol and cholesteryl ester in various tissues including adipose
tissues. To explore the role of HSL in the metabolism of fat and ...
Cited by 26 - Related articles - BL Direct - All 8 versions

Characterization of neuropeptide Y Y2 and Y5 receptor expression in the mouse …


SO Fetissov, LC Byrne, H Hassani, P Ernfors, … - Journal of Comparative Neurology, 2004 - interscience.wiley.com
Neuropeptide Y (NPY) neurons abundantly innervate the hypothalamus, where NPY is
involved in the regulation of a broad range of homeostatic functions. In the
present work we studied NPY Y2 and Y5 receptor (R) gene expression in the ...
Cited by 24 - Related articles - BL Direct - All 2 versions

The new field of neuroskeletal biology


MS Patel, F Elefteriou - Calcified Tissue International, 2007 - Springer
Abstract. The fields of neuroscience and bone biology
haverecentlyconvergedfollowingthediscoverythatbone remodeling is directly
regulated by the brain. This work has defined bone remodeling as one of the ...
Cited by 20 - Related articles - BL Direct - All 6 versions

A strategy to search for common obesity and type 2 diabetes genes

- kuleuven.be [PDF] 
CC Elbers, NC Onland-Moret, L Franke, AG … - Trends in Endocrinology & Metabolism, 2007 - Elsevier
Worldwide, the incidence of type 2 diabetes is rising rapidly, mainly because of
the increase in the incidence of obesity, which is an important risk factor for
this condition. Both obesity and type 2 diabetes are complex genetic traits ...
Cited by 18 - Related articles - All 7 versions

Neuropeptide Y receptor selective ligands in the treatment of obesity

- endojournals.org
MM Kamiji, A Inui - Endocrine reviews, 2007 - Endocrine Soc
Obesity is a serious public health problem throughout the world, affecting both
developed societies and developing countries. The central nervous system has
developed a meticulously interconnected circuitry in order to keep us fed ...
Cited by 18 - Related articles - BL Direct - All 3 versions


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