- ►diabetesjournals.org EA Ryan, BW Paty, PA Senior, D Bigam, E … - Diabetes, 2005 - Am Diabetes Assoc Islet transplantation can restore endogenous β-cell function to subjects with
type 1 diabetes. Sixty-five patients received an islet transplant in Edmonton as
of 1 November 2004. Their mean age was 42.9 ± 1.2 years, their mean ... Cited by 530 - Related articles - All 10 versions
H Kojima, M Fujimiya, K Matsumura, P … - Nature medicine, 2003 - nature.com To explore induced islet neogenesis in the liver as a strategy for the treatment
of diabetes, we used helper-dependent adenovirus (HDAD) to deliver the
pancreatic duodenal homeobox-1 gene (Ipf1; also known as Pdx-1) to ... Cited by 232 - Related articles - BL Direct - All 3 versions
- ►shouxi.net RP Robertson - The New England journal of medicine, 2004 - nejm.highwire.org In 1993 the Diabetes Control and Complications Trial (DCCT) established the
modern standard of care for the medical management of type 1 diabetes mellitus.
1 The DCCT randomly assigned 1441 patients to conventional or intensive ... Cited by 174 - Related articles - All 9 versions
- ►endojournals.org J Gromada, I Franklin, CB Wollheim - Endocrine reviews, 2007 - Endocrine Soc Glucagon, a hormone secreted from the -cells of the endocrine pancreas, is
critical for blood glucose homeostasis. It is the major counterpart to insulin
and is released during hypoglycemia to induce hepatic glucose output. The ... Cited by 60 - Related articles - BL Direct - All 4 versions
P Fiorina, F Folli, P Maffi, C Placidi, M … - Transplantation, 2003 - journals.lww.com Transplantation. Wolters Kluwer Health Logo. All Issues. ... Cited by 51 - Related articles - BL Direct - All 3 versions
- ►diabetesresearch.org [PDF] AM Shapiro, C Ricordi - American Journal of Transplantation, 2004 - ccmjournal.org With cumulative combined data in more than 75 islet recipients from Edmonton,
Miami and Minnesota since 1999, 99% of patients have demonstrated primary graft
function, and 96% remained C-peptide positive at 1 year (3). Rates of ... Cited by 42 - Related articles - BL Direct - All 5 versions
S Merani, A Shapiro - Clinical Science, 2006 - submit.clinsci.org Abbreviations: BMI, body mass index; CD40L, CD40 ligand; CITR, Collaborative
Islet Transplant Registry; CTLA4, cytotoxic T-lymphocyte attenuator protein 4;
CMV, cytomegalovirus; DCCT, Diabetes Control and Complications Trial; DM, ... Cited by 40 - Related articles - Cached - BL Direct - All 12 versions
EA Ryan, BW Paty, PA Senior, AMJ Shapiro - Current Diabetes Reports, 2004 - Springer Introduction Islet transplantation can deliver many benefits: freedom from
hypoglycemia, stable glucose values, insulin indepen- dence, diet
liberalization, improved graft and patient survival after kidney ... Cited by 36 - Related articles - BL Direct - All 3 versions
- ►diabetesjournals.org G Mattsson, L Jansson, A Nordin, A … - Diabetes, 2004 - Am Diabetes Assoc A drawback in pancreatic islet transplantation is the large number of islets
needed to obtain insulin independence in patients with diabetes. This most
likely reflects extensive posttransplantation islet cell death and ... Cited by 34 - Related articles - BL Direct - All 4 versions
JRT Lakey, M Mirbolooki, AMJ Shapiro - … IN MOLECULAR BIOLOGY-CLIFTON THEN TOTOWA …, 2006 - Springer Summary Clinical outcomes of pancreas transplantation were superior to that of
islet transplan- tation until the introduction of the Edmonton protocol.
Significant advances in islet iso- lation and purification technology, ... Cited by 29 - Related articles - BL Direct - All 3 versions
