- ►ahajournals.org J Kim, M Montagnani, KK Koh, MJ Quon - Circulation, 2006 - Am Heart Assoc Endothelial dysfunction contributes to cardiovascular diseases, including
hypertension, atherosclerosis, and coronary artery disease, which are also
characterized by insulin resistance. Insulin resistance is a hallmark of ... Cited by 316 - Related articles - All 9 versions
MA Vincent, LH Clerk, JR Lindner, AL Klibanov … - Diabetes, 2004 - Am Diabetes Assoc Insulin increases glucose disposal into muscle. In addition, in vivo insulin
elicits distinct nitric oxide synthase-dependent vascular responses to increase
total skeletal muscle blood flow and to recruit muscle capillaries (by ... Cited by 99 - Related articles - BL Direct - All 5 versions
JS Yudkin, E Eringa, CDA Stehouwer - The Lancet, 2005 - Elsevier Adipose tissue expresses cytokines that inhibit insulin signalling pathways in
liver and muscle. Obesity also results in impairment of endothelium-dependent
vasodilatation in response to insulin. We propose a vasoregulatory role for ... Cited by 105 - Related articles - All 11 versions
- ►endojournals.org R Muniyappa, M Montagnani, KK Koh, MJ … - Endocrine reviews, 2007 - Endocrine Soc Insulin has important vascular actions to stimulate production of nitric oxide
from endothelium. This leads to capillary recruitment, vasodilation, increased
blood flow, and subsequent augmentation of glucose disposal in classical ... Cited by 99 - Related articles - BL Direct - All 5 versions
- ►ahajournals.org RT de Jongh, EH Serne, RG IJzerman, G de … - Circulation, 2004 - Am Heart Assoc From the Department of Medicine (RTJ, EHS, RGIJ, GV, CDAS), VU University
Medical Center, Amsterdam, Netherlands, and Institute for Cardiovascular
Research, Vrije Universiteit (RTJ, EHS, RGIJ, CDAS), Amsterdam, Netherlands. Cited by 95 - Related articles - BL Direct - All 5 versions
- ►physiology.org MA Vincent, EJ Barrett, JR Lindner, MG Clark, … - American Journal of Physiology- Endocrinology And …, 2003 - Am Physiological Soc We examined the effects of inhibiting nitric oxide synthase with N
-nitro-L-arginine-methyl ester (L-NAME) on total hindlimb blood flow, muscle
microvascular recruitment, and hindlimb glucose uptake during euglycemic ... Cited by 89 - Related articles - BL Direct - All 3 versions
MA Vincent, M Montagnani, MJ Quon - Current Diabetes Reports, 2003 - Springer Insulin has important vascular actions that regulate blood flow, in addition to
its classical actions to coordinate glu- cose homeostasis. Insulin-stimulated
production of nitric oxide in vascular endothelium results in capillary ... Cited by 90 - Related articles - BL Direct - All 2 versions
RT de Jongh, EH Serné, RG IJzerman, G de … - Diabetes, 2004 - Am Diabetes Assoc To test the hypothesis that free fatty acids (FFAs) modulate microvascular
function and that this contributes to obesity-associated insulin resistance,
hypertension, and microangiopathy, we examined the effects of both FFA ... Cited by 71 - Related articles - BL Direct - All 4 versions
- ►uoguelph.ca [PDF] L Zhang, MA Vincent, SM Richards, LH Clerk, S … - Diabetes, 2004 - Am Diabetes Assoc We have reported that insulin exerts two vascular actions in muscle; it both
increases blood flow and recruits capillaries. In parallel
hyperinsulinemic-euglycemic clamp studies, we compared the insulin dose ... Cited by 56 - Related articles - BL Direct - All 5 versions
- ►shouxi.net LH Clerk, MA Vincent, LA Jahn, Z Liu, JR … - Diabetes, 2006 - Am Diabetes Assoc We have previously shown that skeletal muscle capillaries are rapidly recruited
by physiological doses of insulin in both humans and animals. This facilitates
glucose and insulin delivery to muscle, thus augmenting glucose uptake. In ... Cited by 55 - Related articles - BL Direct - All 5 versions
