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Scholar Results 1 - 10 of about 72 citing Wang: Inhibition of the Jak/STAT signaling pathway prevents the high glucose-induced increase.... (0.08 sec) 

Reactive oxygen species-regulated signaling pathways in diabetic nephropathy

- asnjournals.org
HB Lee, MR Yu, Y Yang, Z Jiang, H Ha - Journal of the American …, 2003 - Am Soc Nephrol
Diabetic nephropathy is characterized by excessive deposition of extracellular matrix (ECM)
in the kidney, leading to glomerular mesangial expansion and tubulointerstitial fibrosis. Clinical
studies (1,2) have demonstrated that high blood glucose is the main determinant of ...
Cited by 176 - Related articles - BL Direct - All 7 versions

Microvascular basement membranes in diabetes mellitus


EC Tsilibary - The Journal of Pathology, 2003 - ingentaconnect.com
The alterations in the microvascular system of diabetes mellitus patients are responsible for the
most devastating complications of this widespread disease. In the kidney, the microan- giopathy
leads to thickening of the glomerular capillary basement membrane but also to the ...
Cited by 129 - Related articles - BL Direct - All 7 versions

The pathogenesis of myocardial fibrosis in the setting of diabetic cardiomyopathy

- onlinejacc.org
J Asbun, FJ Villarreal - Journal of the American College of Cardiology, 2006 - Elsevier
Diabetes has emerged as a major threat to worldwide health. The increasing incidence of diabetes
in young individuals is particularly worrisome given that the disease is likely to evolve over a
period of years. In 1972, the existence of a diabetic cardiomyopathy was proposed based ...
Cited by 62 - Related articles - BL Direct - All 21 versions

Angiotensin II blockade prevents hyperglycemia-induced activation of JAK and …

- physiology.org [PDF] 
AK Banes, S Shaw, JA Jenkins, H Redd, F … - American Journal of …, 2003 - Am Physiological Soc
Page 1. Angiotensin II blockade prevents hyperglycemia-induced activation of JAK and
STAT proteins in diabetic rat kidney glomeruli Amy K. Banes, Séan Shaw, John Jenkins,
Heather Redd, Farhad Amiri, David M. Pollock and Mario B. Marrero ...
Cited by 42 - Related articles - BL Direct - All 6 versions

Angiotensin II enhances interleukin-18 mediated inflammatory gene expression in …

- ahajournals.org
S Sahar, RS Dwarakanath, MA Reddy, L Lanting, I … - Circulation …, 2005 - Am Heart Assoc
Vascular smooth muscle cells (VSMCs) express functional interleukin-18 receptors
(IL-18Rs), composed of and ß subunits. These subunits are elevated in VSMCs of atherosclerotic
plaques and can be induced by inflammatory agents in cultured VSMC. Because both ...
Cited by 43 - Related articles - All 10 versions

Reactive oxygen species amplify glucose signalling in renal cells cultured under …


H Ha, HB Lee - Nephrology, 2005 - interscience.wiley.com
SUMMARY: Diabetic nephropathy is characterized by excessive accumulation of extracellular
matrix (ECM) in the kidney. Reactive oxygen species (ROS) play a central role in the ECM synthesis
and degradation in the glomeruli and tubulointerstitium leading to renal fibrosis. High ...
Cited by 39 - Related articles - BL Direct - All 4 versions

Glucose induces de novo lipogenesis in rat muscle satellite cells through a sterol- …

- biologists.org
I Guillet-Deniau, AL Pichard, A Kone, C Esnous, … - Journal of cell …, 2004 - jcs.biologists.org
We previously reported that sterol-regulatory-element-binding-protein-1c (SREBP-1c) mediates
insulin upregulation of genes encoding glycolytic and lipogenic enzymes in rat skeletal
muscle. Here, we assessed whether glucose could regulate gene expression in ...
Cited by 39 - Related articles - BL Direct - All 6 versions

Role of the JAK/STAT signaling pathway in diabetic nephropathy

- physiology.org [PDF] 
MB Marrero, AK Banes-Berceli, DM Stern … - American Journal of …, 2006 - Am Physiological Soc
75 articles, 39 of which you can access free at: This article cites http://ajprenal.physiology.org
/cgi/content/full/290/4/F762#BIBL ... 5 other HighWire hosted articles: This article has been cited
by ... [PDF] [Full Text] [Abstract] , October 1, 2007; 293 (4): F1072-F1082. Am J Physiol ...
Cited by 35 - Related articles - BL Direct - All 4 versions

Effect of antidiabetic medications on microalbuminuria in patients with type 2 …


T Yanagawa, A Araki, K Sasamoto, S Shirabe, T … - Metabolism, 2004 - Elsevier
The progression of diabetes and hypertension complications is associated with
microalbuminuria. Intensive glycemic control prevents or retards microalbuminuria in patients
with type 2 diabetes, but little is known about the respective benefits of different ...
Cited by 29 - Related articles - All 11 versions

The STAT3 DNA-binding domain mediates interaction with NF-{kappa} B p65 and …

- asnjournals.org
Z Yu, BC Kone - Journal of the American Society of Nephrology, 2004 - Am Soc Nephrol
ABSTRACT. Signal transducer and activator of transcription 3 (STAT3) and nuclear factor B
(NF- B) are important transcription factors involved in glomerulonephritis and other inflammatory
processes, including transcription of the inducible nitric oxide synthase (iNOS) gene. The ...
Cited by 27 - Related articles - BL Direct - All 6 versions


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