- ►harvard.edu [PDF] M Stumvoll, BJ Goldstein, TW van Haeften - The Lancet, 2005 - Elsevier Type 2 diabetes mellitus has become an epidemic, and virtually no physician is without patients
who have the disease. Whereas insulin insensitivity is an early phenomenon partly related to
obesity, pancreas β-cell function declines gradually over time already before the onset of ... Cited by 441 - Related articles - All 17 versions
EE Snyder, B Walts, L Pérusse, YC Chagnon, SJ … - update, 2004 - Citeseer WEISNAGEL, TUOMO RANKINEN, AND CLAUDE BOUCHARD. The human obesity gene
map: the 2003 update. Obes Res. 2004;12:369–439. This is the tenth update of the human obesity
gene map, incorporating published results up to the end of October 2003 and continuing ... Cited by 240 - Related articles - View as HTML - BL Direct - All 7 versions
- ►nih.gov MN Weedon, PEH Schwarz, Y Horikawa, N Iwasaki, … - The American Journal of …, 2003 - Elsevier Variation in the calpain-10 gene (CAPN10 [MIM 605286]) was recently linked and associated
with type 2 diabetes mellitus (T2DM) susceptibility (Horikawa et al. 2000). The initial linkage
of T2DM to chromosome 2 was found in a population of Mexican Americans from Starr ... Cited by 127 - Related articles - BL Direct - All 7 versions
- ►nih.gov I Reynisdottir, G Thorleifsson, R Benediktsson, G … - The American Journal of …, 2003 - Elsevier We report a genomewide linkage study of type 2 diabetes (T2D [MIM 125853]) in the Icelandic
population. A list of type 2 diabetics was cross-matched with a computerized genealogical database
clustering 763 type 2 diabetics into 227 families. The diabetic patients and their relatives ... Cited by 97 - Related articles - BL Direct - All 14 versions
- ►nih.gov Y Song, T Niu, JAE Manson, DJ Kwiatkowski, S Liu - The American Journal of …, 2004 - Elsevier The calpain-10 gene (CAPN10) on chromosome 2q37.3 was the first candidate gene for type
2 diabetes (T2D) identified through a genomewide screen and positional cloning. One polymorphism
(UCSNP-43: G→A) and a specific haplotype combination defined by three ... Cited by 77 - Related articles - BL Direct - All 9 versions
H Parikh, L Groop - Reviews in Endocrine & Metabolic Disorders, 2004 - Springer About 150 million people suffer from type 2 diabetes in the world today and it has been predicted
that this num- ber will be doubled within 15 years [1]. It is no longer a disease of the elderly, age
at onset has decreased with the epidemic increase in prevalence. There are large eth- nic ... Cited by 62 - Related articles - BL Direct - All 3 versions
- ►diabetesjournals.org NJ Cox, MG Hayes, CA Roe, T Tsuchiya, GI Bell - Diabetes, 2004 - Am Diabetes Assoc The follow-up studies to the original report of association of variation at calpain 10 (CAPN10)
with type 2 diabetes in the Mexican-American population of Starr County, Texas, encompass
a broad range of science. There are association studies on genetic variation at CAPN10 ... Cited by 47 - Related articles - BL Direct - All 5 versions
- ►endojournals.org E Carlsson, J Fredriksson, L Groop, M … - Journal of Clinical …, 2004 - Endocrine Soc Our aim was to investigate the possible role of the type 2 diabetes susceptibility gene CAPN10
in obesity. A case control study consisting of 235 obese Swedish subjects [body mass index,
40 (35–45) kg/m 2 ] and 235 controls matched for age and gender [body mass index, 22 ... Cited by 41 - Related articles - BL Direct - All 4 versions
- ►endojournals.org A Gonzalez, E Abril, A Roca, MJ Aragon, MJ … - Journal of Clinical …, 2003 - Endocrine Soc THE POLYCYSTIC OVARY syndrome (PCOS) is a common endocrinopathy that is found in about
5–10% of women of reproductive age (1). Specifically in Spain, a prospective study reported
an overall 6.5% prevalence of PCOS (2). Defining PCOS has generated controversies ... Cited by 40 - Related articles - BL Direct - All 4 versions
T Tsuchiya, PEH Schwarz, L del Bosque-Plata, MG … - Molecular Genetics and …, 2006 - Elsevier We conducted pooled and meta-analyses of the association of the calpain-10 gene
(CAPN10) polymorphisms SNP-43, Indel-19 and SNP-63 individually and as haplotypes with
type 2 diabetes (T2D) in 3237 patients and 2935 controls of European ancestry. In the ... Cited by 40 - Related articles - All 3 versions
