CE Mogensen - Journal of internal medicine, 2003 - ingentaconnect.com Over the past decade, there has been considerable focus on the concept of
microalbuminuria, not only because it predicts renal disease in type 1 and type 2 diabetes, but
also because it relates to premature mortality in the diabetic and in the general ... Cited by 145 - Related articles - BL Direct - All 7 versions
H Nakamura, SS Siddiqui, X Shen, AB Malik, JS Pulido, … - Mol Vis, 2004 - molvis.org Methods: TβRII specific siRNAs designed from the human gene sequence were transfected into
cultured human corneal fibroblasts. The protein and transcript levels of the receptor were determined
by immunofluorescence, western blotting, and real time PCR. Immunofluorescence and ... Cited by 79 - Related articles - Cached - All 3 versions
ML Caramori, M Mauer - Current opinion in nephrology and …, 2003 - journals.lww.com Recent findings: There have been advances in the understanding of diabetic nephropathy
pathology. Clearly, structural changes may be advanced before any clinical findings are
apparent. Not all functional consequences of the condition are explained by current ... Cited by 68 - Related articles - BL Direct - All 7 versions
N Abdel Wahab, BS Weston, RM Mason - Experimental cell research, 2005 - Elsevier Transforming growth factor-beta (TGFβ) drives fibrosis in diseases such as diabetic nephropathy
(DN). Connective tissue growth factor (CTGF; CCN2) has also been implicated in this, but the
molecular mechanism is unknown. We show that CTGF enhances the TGFβ/Smad ... Cited by 45 - Related articles - All 3 versions
FN Ziyadeh, K Sharma - Journal of the American Society of Nephrology, 2003 - Am Soc Nephrol The underlying basis of diabetic complications is the result of prevailing levels of
hyperglycemia. This metabolic view became universally accepted only a decade ago thanks
to the definitive results of landmark clinical trials, namely The Diabetes Control and ... Cited by 42 - Related articles - BL Direct - All 4 versions
KG Ewens, RA George, K Sharma, FN Ziyadeh, RS … - Diabetes, 2005 - Am Diabetes Assoc Several lines of evidence, including familial aggregation, suggest that allelic variation contributes
to risk of diabetic nephropathy. To assess the evidence for specific susceptibility genes, we used
the transmission/disequilibrium test (TDT) to analyze 115 candidate genes for linkage ... Cited by 34 - Related articles - BL Direct - All 5 versions
CA Leon, L Raij - Journal of hypertension, 2005 - journals.lww.com Clinical diabetic nephropathy is characterized by an earlier functional phase in which hyperglycaemia
is accompanied by an increased glomerular filtration rate and microalbuminuria; the persistence
of this high-flow and high-pressure state, added to a poor control of hyperglycaemia, ... Cited by 17 - Related articles - All 3 versions
CE Mogensen - Diabetes care, 2003 - Am Diabetes Assoc Diabetic renal disease is still an extremely important and common complication in both type 1
and type 2 diabetic patients. Every clinician and nephrologist knows that diabetic patients constitute
a large proportion of clientele in the dialysis unit, perhaps ∼50% or more, particularly in ... Cited by 12 - Related articles - BL Direct - All 5 versions
J Sakaguchi, S Kyo, T Kanaya, Y Maida, M Hashimoto, … - Gynecologic Oncology, 2005 - Elsevier Real-time PCR analysis using surgical tissue specimens of 27 endometrial cancers and 24 normal
endometria revealed that endometrial cancers had significantly decreased levels of TβRII mRNA
expression (mean level 2.44 ± 2.65), compared to normal endometria (mean level 7.23 ± ... Cited by 9 - Related articles - All 3 versions
