- ►physiology.org WC Stanley, FA Recchia, GD Lopaschuk - Physiological reviews, 2005 - Am Physiological Soc The alterations in myocardial energy substrate metabolism that occur in heart
failure, and the causes and consequences of these abnormalities, are poorly
understood. There is evidence to suggest that impaired substrate metabolism ... Cited by 310 - Related articles - All 8 versions
- ►physiology.org HV Carey, MT Andrews, SL Martin - Physiological reviews, 2003 - Am Physiological Soc The ability to hibernate is arguably the most dramatic example of phenotypic
plasticity displayed by mammals. Each year mammalian hibernators undergo a
complex suite of morphological, physiological, and behavioral changes in ... Cited by 152 - Related articles - BL Direct - All 8 versions
- ►physiology.org MC Sugden, MJ Holness - American Journal of Physiology- Endocrinology And …, 2003 - Am Physiological Soc The mitochondrial pyruvate dehydrogenase complex (PDC) catalyzes the oxidative
decarboxylation of pyruvate, linking glycolysis to the tricarboxylic acid cycle
and fatty acid (FA) synthesis. Knowledge of the mechanisms that regulate ... Cited by 100 - Related articles - BL Direct - All 3 versions
- ►nih.gov [PDF] T Furuyama, K Kitayama, H Yamashita, N … - Biochemical Journal, 2003 - pubmedcentral.nih.gov A forkhead-type transcription factor, DAF-16, is located in the most downstream
part of the insulin signalling pathway via PI3K (phosphoinositide 3-kinase). It
is essential for the extension of life-span and is also involved in dauer ... Cited by 95 - Related articles - BL Direct - All 7 versions
- ►nih.gov AR Wende, JM Huss, PJ Schaeffer, V Giguere, … - Molecular and Cellular Biology, 2005 - Am Soc Microbiol The transcriptional coactivator PGC-1 is a key regulator of energy metabolism,
yet little is known about its role in control of substrate selection. We found
that physiological stimuli known to induce PGC-1 expression in skeletal ... Cited by 90 - Related articles - All 5 versions
M Holness, M Sugden - Biochemical Society Transactions, 2003 - bst.portlandpress.com PDC (pyruvate dehydrogenase complex) catalyses the oxidative decarboxylation of
pyruvate, linking glycolysis to the tricarboxylic acid cycle. Regulation of PDC
determines and reflects substrate preference and is critical to the ... Cited by 84 - Related articles - Cached - BL Direct - All 9 versions
- ►loc.gov [PDF] DA Bender, 2003 - books.google.com Nutritional Biochemistry of the Vitamins SECOND ED1T1ON The vitamins are a
chemically disparate group of compounds whose only common feature is that they
are dietary essentials that are required in small amounts for the normal ... Cited by 81 - Related articles - All 8 versions
JW Newman, C Morisseau, BD Hammock - Progress in lipid research, 2005 - Elsevier The epoxide hydrolases (EHs) are enzymes present in all living organisms, which
transform epoxide containing lipids by the addition of water. In plants and
animals, many of these lipid substrates have potent biologically ... Cited by 69 - Related articles - All 4 versions
HS Kwon, B Huang, TG Unterman, RA Harris - Diabetes, 2004 - Am Diabetes Assoc Starvation and diabetes increase pyruvate dehydrogenase kinase-4 (PDK4)
expression, which conserves gluconeogenic substrates by inactivating the
pyruvate dehydrogenase complex. Mechanisms that regulate PDK4 gene ... Cited by 58 - Related articles - BL Direct - All 4 versions
