TP DiLorenzo, DV Serreze - Immunol. Rev, 2005 - interscience.wiley.com Summary: Type 1 diabetes (T1D) in both humans and nonobese diabetic (NOD) mice
is a T-cell-mediated autoimmune disease in which the insulin-producing
pancreatic islet β-cells are selectively eliminated. As a result, glucose ... Cited by 35 - Related articles - All 7 versions
- ►jimmunol.org MJ Perone, S Bertera, ZS Tawadrous, WJ … - The Journal of Immunology, 2006 - Am Assoc Immnol Type 1 diabetes (T1D) is a disease caused by the destruction of the cells of the
pancreas by activated T cells. Dendritic cells (DC) are the APC that initiate
the T cell response that triggers T1D. However, DC also participate in T ... Cited by 29 - Related articles - BL Direct - All 5 versions
- ►jimmunol.org DV Serreze, TM Holl, MP Marron, RT Graser, … - The Journal of Immunology, 2004 - Am Assoc Immnol Development of autoreactive CD4 T cells contributing to type 1 diabetes (T1D) in
both humans and nonobese diabetic (NOD) mice is either promoted or dominantly
inhibited by particular MHC class II variants. In addition, it is now clear ... Cited by 28 - Related articles - BL Direct - All 4 versions
Y Yang, P Santamaria - Diabetologia, 2003 - Springer Type 1 diabetes results from a genetically and immu- nologically complex
autoimmune process that is spe- cifically directed against the pancreatic beta
cells. Non-obese diabetic mice spontaneously develop a form of autoimmune ... Cited by 21 - Related articles - BL Direct - All 4 versions
- ►jimmunol.org Y Yan, T Devos, L Yu, G Xia, O Rutgeerts, J … - The Journal of Immunology, 2003 - Am Assoc Immnol Thymus transplantation is a promising strategy to induce xenotolerance, but may
also induce an autoimmune syndrome (AIS). The pathogenesis of this AIS was
explored using nude rats as recipients. Thymus grafts consisted of fetal ... Cited by 14 - Related articles - BL Direct - All 7 versions
C LeGuern - Trends in immunology, 2003 - Elsevier The role of MHC class II in the control of T-cell responses to self and foreign
antigens is still unclear. No unifying principle yet explains how class II
molecules repress immunity to self or allogeneic antigens. Our recent data ... Cited by 9 - Related articles - All 4 versions
Y Yang, P Santamaria - Journal of Autoimmunity, 2004 - Elsevier Insulin-dependent diabetes mellitus (Type 1 Diabetes, T1D) in humans and
nonobese diabetic (NOD) mice is the result of a chronic autoimmune process
directed against the pancreatic beta cells [1 and 2]. There is extensive ... Cited by 4 - Related articles - All 3 versions
- ►jimmunol.org A Ueno, S Cho, L Cheng, Z Wang, B Wang, Y … - The Journal of Immunology, 2005 - Am Assoc Immnol Polymorphism of MHC and MHC-linked genes is tightly associated with
susceptibility to type 1 diabetes (T1D) in human and animal models. Despite the
extensive studies, however, the role of MHC and MHC-linked genes expressed ... Cited by 3 - Related articles - BL Direct - All 5 versions
H Tsui, S Winer, G Jakowsky, HM Dosch - Reviews in Endocrine & Metabolic Disorders, 2003 - Springer Key Words. type 1 diabetes, autoimmunity, prediabetes, Schwann cells ... Type 1
diabetes (T1D) is characterized by perma- nent insulin deficiency due to the
lymphocyte mediated autoimmune-destruction of insulin producing pancreatic ... Cited by 1 - Related articles - All 3 versions
