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Scholar Results 1 - 10 of about 28 citing Gurr: A Reg family protein is overexpressed in islets from a patient with new-onset type.... (0.09 sec) 

IL-6 in autoimmune disease and chronic inflammatory proliferative disease


K Ishihara, T Hirano - Cytokine and Growth Factor Reviews, 2002 - Elsevier
Interleukin 6 (IL-6), which was originally identified as a B-cell
differentiation factor, is now known to be a multifunctional cytokine that
regulates the immune response, hematopoiesis, the acute phase response, and ...
Cited by 210 - Related articles - All 10 versions

Interleukin-6 and diabetes

- shouxi.net
OP Kristiansen, T Mandrup-Poulsen - Diabetes, 2005 - Am Diabetes Assoc
Inflammatory mechanisms play a key role in the pathogenesis of type 1 diabetes.
Individuals who progress to type 2 diabetes display features of low-grade
inflammation years in advance of disease onset. This low-grade inflammation ...
Cited by 72 - Related articles - BL Direct - All 5 versions

A comprehensive guide to antibody and T-cell responses in type 1 diabetes


SM Lieberman, TP DiLorenzo - Tissue Antigens, 2003 - interscience.wiley.com
Abstract: Type 1 diabetes (T1D) is an organ-specific autoimmune disease in which
the insulin-producing β cells in the pancreatic islets are selectively
eliminated. T cells specific for β-cell antigens are the mediators of this ...
Cited by 60 - Related articles - BL Direct - All 5 versions

A pentadecapeptide fragment of islet neogenesis-associated protein increases beta-cell …


L Rosenberg, M Lipsett, JW Yoon, M Prentki, R … - Annals of surgery, 2004 - pubmedcentral.nih.gov
From the *Department of Surgery, McGill University, Montreal, Quebec, Canada;
†Julia Macfarlane Diabetes Research Center, University of Calgary, Calgary,
Alberta, Canada; the ‡Departments of Nutrition and Biochemistry, ...
Cited by 58 - Related articles - BL Direct - All 4 versions

Progression to Islet Destruction in a Cyclophosphamide-Induced Transgenic Model


M Matos, R Park, D Mathis, C Benoist - Diabetes, 2004 - Am Diabetes Assoc
Type 1 diabetes appears to progress not as an uncontrolled autoimmune attack on
the pancreatic islet ß-cells, but rather in a highly regulated manner.
Leukocytic infiltration of the pancreatic islets by autoimmune cells, or ...
Cited by 28 - Related articles - BL Direct - All 4 versions

The multifunctional family of secreted proteins containing a C-type lectin-like domain linked …


JL Iovanna, JC Dagorn - BBA-General Subjects, 2005 - Elsevier
PSP/Lithostathine/PTP/regI, PAP/p23/HIP, reg1L, regIV and “similar to PAP”
are the members of a multifunctional family of secreted proteins containing a
C-type lectin-like domain linked to a short N-terminal peptide. The ...
Cited by 21 - Related articles - All 4 versions

Dynamic interaction between T cell-mediated beta cell damage and beta cell repair in the …

- physiology.org [PDF] 
SS Vukkadapu, JM Belli, K Ishii, AG Jegga, JJ … - Physiological Genomics, 2005 - Am Physiological Soc
Page 1. Dynamic interaction between T cell-mediated beta cell damage and beta cell
repair in the run-up to autoimmune diabetes of the NOD mouse ...
Cited by 21 - Related articles - All 4 versions

[PDF] Gene expression profiling in islet biology and diabetes research


DMR Rev - Diabetes Metab Res Rev, 2003 - cms1.daegu.ac.kr
Diabetes Metab Res Rev 2003; 19: 32–42. Published online 17 October 2002 in
Wiley InterScience (www.interscience.wiley.com). DOI: 10.1002/dmrr.331 ... Gene
expression profiling in islet biology and ... Ernesto Bernal-Mizrachi ...
Cited by 18 - Related articles - View as HTML - BL Direct - All 5 versions

Involvement of eotaxin, eosinophils, and pancreatic predisposition in development of type 1 …

- jimmunol.org
MJ Hessner, X Wang, L Meyer, R Geoffrey, S … - The Journal of Immunology, 2004 - Am Assoc Immnol
Allergy and autoimmunity are both examples of deregulated immunity characterized
by inflammation and injury of targeted tissues that have until recently been
considered disparate disease processes. However, recent findings have ...
Cited by 15 - Related articles - BL Direct - All 7 versions

T-cell epitopes in type 1 diabetes


C Panagiotopoulos, JD Trudeau, R Tan - Current Diabetes Reports, 2004 - Springer
Introduction Type 1 diabetes (T1D) is an autoimmune disease that results from
destruction of insulin-producing pancreatic β cells in the islets of
Langerhans. In genetically predisposed individu- als, as-yet unidentified ...
Cited by 12 - Related articles - BL Direct - All 2 versions


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