- ►endojournals.org JM Fernandez-Real, W Ricart - Endocrine Reviews, 2003 - Endocrine Soc Insulin resistance is increasingly recognized as a chronic, low-level,
inflammatory state. Hyperinsulinemia and insulin action were initially proposed
as the common preceding factors of hypertension, low high-density ... Cited by 431 - Related articles - BL Direct - All 5 versions
- ►nih.gov SE Shoelson, J Lee, AB Goldfine - Journal of Clinical Investigation, 2006 - Am Soc Clin Investig Over a hundred years ago, high doses of salicylates were shown to lower glucose
levels in diabetic patients. This should have been an important clue to link
inflammation to the pathogenesis of type 2 diabetes (T2D), but the ... Cited by 421 - Related articles - BL Direct - All 11 versions
JC Pickup - Diabetes care, 2004 - Am Diabetes Assoc There is increasing evidence that an ongoing cytokine-induced acute-phase
response (sometimes called low-grade inflammation, but part of a widespread
activation of the innate immune system) is closely involved in the ... Cited by 365 - Related articles - BL Direct - All 8 versions
- ►physiology.org AMW Petersen, BK Pedersen - Journal of Applied Physiology, 2005 - Am Physiological Soc Regular exercise offers protection against all-cause mortality, primarily by
protection against cardiovascular disease and Type 2 diabetes mellitus. The
latter disorders have been associated with chronic low-grade systemic ... Cited by 323 - Related articles - All 10 versions
J Spranger, A Kroke, M Möhlig, K Hoffmann, … - Diabetes, 2003 - Am Diabetes Assoc A subclinical inflammatory reaction has been shown to precede the onset of type
2 (non-insulin-dependent) diabetes. We therefore examined prospectively the
effects of the central inflammatory cytokines interleukin (IL)-1β, IL-6, ... Cited by 320 - Related articles - BL Direct - All 5 versions
BB Duncan, MI Schmidt, JS Pankow, CM … - Diabetes, 2003 - Am Diabetes Assoc To examine the association of low-grade systemic inflammation with diabetes, as
well as its heterogeneity across subgroups, we designed a case-cohort study
representing the ∼9-year experience of 10,275 Atherosclerosis Risk in ... Cited by 234 - Related articles - BL Direct - All 6 versions
RF Grimble - Current Opinion in Clinical Nutrition & Metabolic Care, 2002 - journals.lww.com Recent findings: Population studies show a strong association between indices of
inflammation, and abnormal lipid and carbohydrate metabolism, obesity and
atherosclerosis. TNF-α is produced, by cells of the immune system and by ... Cited by 218 - Related articles - BL Direct - All 7 versions
- ►diabetesjournals.org B Vozarova, N Stefan, RS Lindsay, A Saremi, … - Diabetes, 2002 - Am Diabetes Assoc It has been proposed that liver dysfunction may contribute to the development of
type 2 diabetes. The aim of the present study was to examine whether elevated
hepatic enzymes (alanine aminotransferase [ALT], aspartate aminotransferase ... Cited by 199 - Related articles - BL Direct - All 7 versions
- ►diabetesjournals.org J Krakoff, T Funahashi, CDA Stehouwer, CG … - Diabetes care, 2003 - Am Diabetes Assoc RESEARCH DESIGN AND METHODS—Participants with normal glucose tolerance at
baseline were selected. Case subjects (who later developed type 2 diabetes), and
control subjects (n = 71 pairs) were matched for BMI, age, and sex. ... Cited by 181 - Related articles - BL Direct - All 7 versions
ES Ford - Atherosclerosis, 2003 - Elsevier To examine the association between the metabolic syndrome and C-reactive
protein, fibrinogen, and leukocyte count, the author did a cross-sectional
analysis of data from 8570 participants aged ≥20 years from the Third ... Cited by 174 - Related articles - All 13 versions
