- ►biosino.org [PDF] - Free from Publisher RJ Sigal, GP Kenny, DH Wasserman, C … - Diabetes care, 2004 - Am Diabetes Assoc For decades, exercise has been considered a cornerstone of diabetes management,
along with diet and medication. However, high-quality evidence on the importance
of exercise and fitness in diabetes was lacking until recent years. The ... Cited by 374 - Related articles - BL Direct - All 16 versions
- ►physiology.org K Sakamoto, LJ Goodyear - Journal of Applied Physiology, 2002 - Am Physiological Soc Physical exercise is a significant stimulus for the regulation of multiple
metabolic and transcriptional processes in skeletal muscle. For example,
exercise increases skeletal muscle glucose uptake, and, after exercise, ... Cited by 151 - Related articles - BL Direct - All 3 versions
- ►physiology.org AJ Rose, EA Richter - Physiology, 2005 - Am Physiological Soc During dynamic exercise, the turnover of ATP in skeletal muscle increases
greatly and is fuelled by the catabolism of carbohydrates (intramuscular
glycogen, blood glucose) and fatty acids (intramuscular triglycerides, ... Cited by 60 - Related articles - BL Direct - All 4 versions
- ►jbc.org J Giraud, R Leshan, YH Lee, MF White - Journal of Biological Chemistry, 2004 - ASBMB Ser/Thr phosphorylation of insulin receptor substrate IRS-1 regulates insulin
signaling, but the relevant phosphorylated residues and their potential
functions during insulin-stimulated signal transduction are difficult to ... Cited by 58 - Related articles - BL Direct - All 6 versions
- ►physiology.org JFP Wojtaszewski, JN Nielsen, EA Richter - Journal of Applied Physiology, 2002 - Am Physiological Soc After a single bout of exercise, insulin action is increased in the muscles that
were active during exercise. The increased insulin action has been shown to
involve glucose transport, glycogen synthesis, and glycogen synthase (GS) ... Cited by 53 - Related articles - BL Direct - All 3 versions
- ►nih.gov X Dong, S Park, X Lin, K Copps, X Yi, MF … - Journal of Clinical Investigation, 2005 - Am Soc Clin Investig Insulin receptor substrates, including Irs1 and Irs2, integrate insulin and IGF
receptor signals with heterologous pathways to coordinate growth and metabolism.
Since Irs2 is thought to be especially important in hepatic nutrient ... Cited by 36 - Related articles - BL Direct - All 12 versions
JFP Wojtaszewski, SB Jorgensen, C Frosig, C … - Acta Physiologica Scandinavica, 2003 - interscience.wiley.com After the discovery and clinical use of insulin for treatment of diabetes it
became clear that some of the biological effect of insulin was dependent on the
circumstances under which it was given. Relevant for this review is the ... Cited by 34 - Related articles - BL Direct - All 4 versions
JA Hawley, SJ Lessard - Acta Physiologica, 2008 - interscience.wiley.com Individuals with insulin resistance are characterized by impaired insulin action
on whole-body glucose uptake, in part due to impaired insulin-stimulated glucose
uptake into skeletal muscle. A single bout of exercise increases skeletal ... Cited by 35 - Related articles - BL Direct - All 3 versions
- ►physiology.org AE Civitarese, MKC Hesselink, AP Russell, E … - American Journal of Physiology- Endocrinology And …, 2005 - Am Physiological Soc Ingestion of carbohydrate during exercise may blunt the stimulation of fat
oxidative pathways by raising plasma insulin and glucose concentrations and
lowering plasma free fatty acid (FFA) levels, thereby causing a marked ... Cited by 17 - Related articles - BL Direct - All 4 versions