- ►diabetesjournals.org JL Gross, MJ de Azevedo, SP Silveiro, LH … - Diabetes Care, 2005 - Am Diabetes Assoc Diabetic nephropathy is the leading cause of kidney disease in patients starting
renal replacement therapy and affects ∼40% of type 1 and type 2 diabetic
patients. It increases the risk of death, mainly from cardiovascular ... Cited by 214 - Related articles - All 18 versions
ML Caramori, M Mauer - Current opinion in nephrology and hypertension, 2003 - journals.lww.com Recent findings: There have been advances in the understanding of diabetic
nephropathy pathology. Clearly, structural changes may be advanced before any
clinical findings are apparent. Not all functional consequences of the ... Cited by 68 - Related articles - BL Direct - All 7 versions
- ►diabetesjournals.org S Chen, Y Kasama, JS Lee, B Jim, M Marin, … - Diabetes, 2004 - Am Diabetes Assoc Podocyte-derived vascular endothelial growth factor (VEGF) is upregulated in
diabetes and may contribute to albuminuria. Although believed to act upon the
glomerular endothelium, VEGF may have pronounced effects on the podocyte ... Cited by 51 - Related articles - BL Direct - All 4 versions
S Chen, M Carmen Iglesias-de la Cruz, B Jim … - Biochemical and Biophysical Research …, 2003 - Elsevier Treatment with a neutralizing anti-transforming growth factor-β (TGF-β)
antibody can prevent the development of diabetic nephropathy in the db/db mouse,
a model of type 2 diabetes. However, it is unknown whether anti-TGF-β ... Cited by 51 - Related articles - BL Direct - All 5 versions
- ►amjpathol.org D Fraser, N Brunskill, T Ito, A Phillips - American Journal of Pathology, 2003 - ASIP We have recently reported increased transforming growth factor (TGF)-ß1 gene
transcription in proximal tubular cells within 12 hours of exposure to 25 mmol/L
D-glucose, with a requirement for a second stimulus such as ... Cited by 51 - Related articles - BL Direct - All 4 versions
P Beisswenger, S Howell, R Nelson, M Mauer … - Biochemical Society Transactions, 2003 - bst.portlandpress.com The factors responsible for variable susceptibility to diabetic nephropathy are
not clear. According to the non-enzymatic glycation hypothesis, diabetes-related
tissue damage occurs due to a complex mixture of toxic products, including ... Cited by 48 - Related articles - Cached - BL Direct - All 9 versions
- ►asnjournals.org SH Sung, FN Ziyadeh, A Wang, PE Pyagay, … - Journal of the American Society of Nephrology, 2006 - Am Soc Nephrol For investigation of how the vascular endothelial growth factor (VEGF) system
participates in the pathogenesis of diabetic kidney disease, type 2 diabetic
db/db and control db/m mice were treated intraperitoneally with vehicle or ... Cited by 44 - Related articles - BL Direct - All 5 versions
- ►oxfordjournals.org S Chen, JS Lee, MC Iglesias-De La Cruz, A … - Nephrology Dialysis Transplantation, 2005 - ERA-EDTA Results. AngII 10 –10 M was found to stimulate the production of 3(IV)
collagen significantly in as short a time as 3 h. The expression of 3(IV)
collagen was influenced by the TGF-ß system, but AngII did not increase ... Cited by 43 - Related articles - All 5 versions
- ►shouxi.net PJ Beisswenger, KS Drummond, RG Nelson, … - Diabetes, 2005 - Am Diabetes Assoc Dicarbonyl and oxidative stress may play important roles in the development of
diabetes complications, and their response to hyperglycemia could determine
individual susceptibility to diabetic nephropathy. This study examines the ... Cited by 44 - Related articles - BL Direct - All 5 versions
- ►diabetesjournals.org R Klein, B Zinman, R Gardiner, S Suissa, SM … - Diabetes, 2005 - Am Diabetes Assoc Few epidemiological data exist regarding the correlation of anatomic measures of
diabetic retinopathy and nephropathy, especially early in the disease processes.
The aim of this study was to examine the association of severity of ... Cited by 39 - Related articles - All 5 versions
