- ►nih.gov L Wilson-Fritch, S Nicoloro, M Chouinard, … - Journal of Clinical …, 2004 - Am Soc Clin Investig Adipose tissue plays a central role in the control of energy homeostasis through the storage and
turnover of triglycerides and through the secretion of factors that affect satiety and fuel
utilization. Agents that enhance insulin sensitivity, such as rosiglitazone, appear to exert ... Cited by 152 - Related articles - BL Direct - All 15 versions
L Reshef, Y Olswang, H Cassuto, B Blum, CM … - Journal of Biological …, 2003 - ASBMB During fasting in all mammals, triglyceride stored in adipose tissue is hydrolyzed by a
hormone-sensitive lipase to produce free fatty acids (FFA) 1 and glycerol. Detailed studies of
the balance of glycerol and FFA released from white adipose tissue (WAT) during ... Cited by 112 - Related articles - BL Direct - All 8 versions
- ►jlr.org TM Larsen, S Toubro, A Astrup - The Journal of Lipid Research, 2003 - ASBMB Dietary supplements containing conjugated linoleic acid (CLA) are widely promoted as weight
loss agents available over the counter and via the Internet. In this review, we evaluate the efficacy
and safety of CLA supplementation based on peer-reviewed published results from ... Cited by 90 - Related articles - BL Direct - All 8 versions
- ►jbc.org Y Sun, S Liu, S Ferguson, LQ Wang, P Klepcyk, JS … - Journal of Biological …, 2002 - ASBMB The ability of insulin to suppress gluconeogenesis in type II diabetes mellitus is impaired;
however, the cellular mechanisms for this insulin resistance remain poorly understood. To address
this question, we generated transgenic (TG) mice overexpressing the ... Cited by 74 - Related articles - BL Direct - All 5 versions
- ►alfediam.org [PDF] V Large, O Peroni, D Letexier, H Ray, M Beylot - Diabetes and Metabolism, 2004 - Elsevier Adipose tissue is considered as the body's largest storage organ for energy in the form of
triacylglycerols, which are mobilized through lipolysis process, to provide fuel to other organs
and to deliver substrates to liver for gluconeogenesis (glycerol) and lipoprotein synthesis ( ... Cited by 72 - Related articles - All 4 versions
- ►nih.gov KH Kim, L Zhao, Y Moon, C Kang, … - Proceedings of the …, 2004 - National Acad Sciences Adipocyte-specific secretory factor (ADSF)/resistin is a small cysteine-rich protein secreted from
adipose tissue that belongs to a gene family found in inflammatory zone (FIZZ) or found in
resistin-like molecule (RELM). ADSF has been implicated in modulating adipogenesis ... Cited by 66 - Related articles - BL Direct - All 9 versions
- ►jbc.org T Jiang, Z Wang, G Proctor, S Moskowitz, SE … - Journal of Biological …, 2005 - ASBMB Obesity and metabolic syndrome are associated with glomerulosclerosis and proteinuria, but
the mechanisms are not known. The purpose of this study was to determine if there is altered
renal lipid metabolism and increased expression of sterol regulatory element-binding ... Cited by 58 - Related articles - BL Direct - All 5 versions
- ►diabetesjournals.org HC Chen, SJ Stone, P Zhou, KK Buhman, RV Farese - Diabetes, 2002 - Am Diabetes Assoc Acyl coenzyme A:diacylglycerol acyltransferase 1 (DGAT1) is one of two DGAT enzymes known
to catalyze the final step in mammalian triglyceride synthesis. Mice deficient in DGAT1 are resistant
to obesity and have enhanced insulin sensitivity. To understand better the relationship ... Cited by 52 - Related articles - BL Direct - All 7 versions
JA Villena, B Viollet, F Andreelli, A Kahn, S Vaulont, HS … - Diabetes, 2004 - Am Diabetes Assoc AMP-activated protein kinase (AMPK) is considered as a cellular energy sensor that regulates
glucose and lipid metabolism by phosphorylating key regulatory enzymes. Despite the major
role of adipose tissue in regulating energy partitioning in the organism, the role of AMPK ... Cited by 51 - Related articles - BL Direct - All 6 versions
- ►physiology.org CL Brand, J Sturis, CF Gotfredsen, J … - American Journal of …, 2003 - Am Physiological Soc Improvement of insulin sensitivity and lipid and glucose metabolism by coactivation of both nuclear
peroxisome proliferator-activated receptor (PPAR) and PPAR potentially provides beneficial
effects over existing PPAR and preferential drugs, respectively, in treatment of type 2 ... Cited by 49 - Related articles - BL Direct - All 4 versions
