Y Dor, J Brown, OI Martinez, DA Melton - Nature, 2004 - molecool.wustl.edu How tissues generate and maintain the correct number of cells is a fundamental
problem in biology. In principle, tissue turnover can occur by the
differentiation of stem cells, as is well documented for blood, skin and ... Cited by 786 - Related articles - View as HTML - BL Direct - All 26 versions
- ►endojournals.org PL Brubaker, DJ Drucker - Endocrinology, 2004 - Endocrine Soc Gut peptides exert diverse effects regulating satiety, gastrointestinal motility
and acid secretion, epithelial integrity, and both nutrient absorption and
disposal. These actions are initiated by activation of specific G protein- ... Cited by 216 - Related articles - BL Direct - All 7 versions
- ►physiology.org L Bouwens, I Rooman - Physiological reviews, 2005 - Am Physiological Soc Beta-cell mass regulation represents a critical issue for understanding
diabetes, a disease characterized by a near-absolute (type 1) or relative (type
2) deficiency in the number of pancreatic beta cells. The number of islet ... Cited by 115 - Related articles - BL Direct - All 6 versions
K Timper, D Seboek, M Eberhardt, P Linscheid, … - Biochemical and biophysical research communications, 2006 - Elsevier Mesenchymal stem cells (MSC) from mouse bone marrow were shown to adopt a
pancreatic endocrine phenotype in vitro and to reverse diabetes in an animal
model. MSC from human bone marrow and adipose tissue represent very similar ... Cited by 99 - Related articles - All 5 versions
L Baeyens, S De Breuck, J Lardon, JK … - Diabetologia, 2005 - Springer Abstract Aims/hypothesis: Transplantation of insulin- producing beta cells from
donors can cure diabetes, but they are available in insufficient quantities. In
this study, we investigated the possibility of generating insulin- ... Cited by 93 - Related articles - All 6 versions
- ►nih.gov DJ Drucker - Journal of Clinical Investigation, 2007 - Am Soc Clin Investig The gastrointestinal tract has a crucial role in the control of energy
homeostasis through its role in the digestion, absorption, and assimilation of
ingested nutrients. Furthermore, signals from the gastrointestinal tract ... Cited by 82 - Related articles - BL Direct - All 11 versions
- ►tufts.edu [PDF] LL Baggio, DJ Drucker, 2006 - Annual Reviews Type 2 diabetes is characterized by hyperglycemia resulting from insulin
resistance in the setting of inadequate β-cell compensation. Currently
available therapeutic agents lower blood glucose through multiple ... Cited by 76 - Related articles - BL Direct - All 10 versions
A Aly, A Shulkes, GS Baldwin - BBA-Reviews on Cancer, 2004 - Elsevier The gastrointestinal peptide hormones gastrin and cholecystokinin (CCK) are well
known for their ability to stimulate gastric acid secretion and pancreatic
enzyme secretion, respectively. The suggestion that gastrin and CCK might ... Cited by 71 - Related articles - All 3 versions
- ►endojournals.org WL Suarez-Pinzon, JRT Lakey, SJ Brand, A … - Journal of Clinical Endocrinology & Metabolism, 2005 - Endocrine Soc Pancreatic islet transplantation is a viable treatment for type 1 diabetes, but
is limited by human donor tissue availability. The combination of epidermal
growth factor (EGF) and gastrin induces islet ß-cell neogenesis from ... Cited by 68 - Related articles - All 5 versions
I Rooman, L Bouwens - Diabetologia, 2004 - Springer Aims/hypothesis. Increasing beta-cell mass and/or function could restore glucose
homeostasis in diabetes mellitus. Hitherto, trophic factors for beta-cell regen-
eration after toxic events have been difficult to identi- fy. We evaluated ... Cited by 63 - Related articles - BL Direct - All 4 versions
