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Scholar Results 1 - 10 of about 112 citing Segel: Hypoglycemia-associated autonomic failure in advanced type 2 diabetes. (0.07 sec) 

Hypoglycemia in diabetes

- diabetesjournals.org
PE Cryer, SN Davis, H Shamoon - Diabetes Care, 2003 - Am Diabetes Assoc
Iatrogenic hypoglycemia causes recurrent morbidity in most people with type 1 diabetes and
many with type 2 diabetes, and it is sometimes fatal. The barrier of hypoglycemia generally precludes
maintenance of euglycemia over a lifetime of diabetes and thus precludes full realization ...
Cited by 373 - Related articles - All 8 versions

Hypoglycaemia: The limiting factor in the glycaemic management of Type I and …


P Cryer - Diabetologia, 2002 - Springer
Hypoglycaemia is the limiting factor in the glycaemic management of diabetes. Iatrogenic hypoglycaemia
is typically the result of the interplay of insulin excess and compromised glucose counterregulation
in Type I (insulin-dependent) diabetes mellitus. Insulin concen- trations do not decrease ...
Cited by 225 - Related articles - BL Direct - All 6 versions

Diverse causes of hypoglycemia-associated autonomic failure in diabetes

- shouxi.net
PE Cryer - New England Journal of Medicine, 2004 - content.nejm.org
In this article, I discuss the clinical problem of hypoglycemia in diabetes from the perspective
of pathophysiology. First, the syndromes of defective glucose counterregulation and hypoglycemia
without warning symptoms (known as "hypoglycemia unawareness") are described, ...
Cited by 156 - Related articles - BL Direct - All 6 versions

The continuous glucose monitoring system is useful for detecting unrecognized …

- diabetesjournals.org
A Chico, P Vidal-Ríos, M Subirà, A Novials - Diabetes Care, 2003 - Am Diabetes Assoc
RESULTS—The CGMS detected unrecognized hypoglycemias in 62.5% of the type 1 diabetic
patients and in 46.6% of the type 2 diabetic patients. We found that 73.7% of all events occurred
at night. HbA 1c concentrations decreased significantly in both the group of type 1 ...
Cited by 121 - Related articles - BL Direct - All 7 versions

Hypoglycemia in type 2 diabetes

- diabetesjournals.org
NN Zammitt, BM Frier - Diabetes Care, 2005 - Am Diabetes Assoc
The importance of strict glycemic control to limit the risk of diabetic vascular complications is
indisputable, but many barriers obstruct its attainment. Hypoglycemia is recognized to be a major
limitation in achieving good control in type 1 diabetes (1) but has been considered to be a ...
Cited by 89 - Related articles - All 6 versions

Mechanisms of hypoglycemia-associated autonomic failure and its component …


PE Cryer - Diabetes, 2005 - Am Diabetes Assoc
Iatrogenic hypoglycemia is a problem for people with diabetes. It causes recurrent morbidity,
and sometimes death, as well as a vicious cycle of recurrent hypoglycemia, precluding maintenance
of euglycemia over a lifetime of diabetes. Improved therapeutic approaches that will ...
Cited by 75 - Related articles - BL Direct - All 7 versions

Hypoglycemia-associated autonomic failure in diabetes

- physiology.org
PE Cryer - American Journal of Physiology- Endocrinology And …, 2001 - Am Physiological Soc
Hypoglycemia is the limiting factor in the glycemic management of diabetes. The concept of
hypoglycemia-associated autonomic failure (HAAF) in diabetes posits that recent antecedent
iatrogenic hypoglycemia causes both defective glucose counterregulation (by reducing ...
Cited by 59 - Related articles - BL Direct - All 3 versions

Loss of the decrement in intraislet insulin plausibly explains loss of the glucagon …


B Raju, PE Cryer - Diabetes, 2005 - Am Diabetes Assoc
The intraislet insulin hypothesis for the signaling of the glucagon secretory response to hypoglycemia
states that a decrease in arterial glucose → a decrease in β-cell insulin secretion → a decrease
in tonic α-cell inhibition by insulin → an increase in α-cell glucagon secretion. To test this ...
Cited by 60 - Related articles - All 6 versions

Hypoglycemia as a barrier to glycemic control


S Davis, MD Alonso - Journal of Diabetes and its Complications, 2004 - Elsevier
Diabetes mellitus is associated with significant morbidity and mortality derived from long-term
microvascular and macrovascular complications of chronic hyperglycemia. The Diabetes Control
and Complications Trial (DCCT) and the UK Prospective Diabetes Study (UKPDS) have ...
Cited by 59 - Related articles - All 12 versions

Frequency and predictors of hypoglycaemia in Type1 and insulin-treated Type2 …


LA Donnelly, AD Morris, BM Frier, JD Ellis, PT … - Diabetic …, 2005 - interscience.wiley.com
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Cited by 57 - Related articles - All 6 versions


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