M Zhou, DA Lucas, KC Chan, HJ Issaq, EF … - Electrophoresis, 2004 - interscience.wiley.com The protein content of human serum is composed of a millieu of proteins from
almost every type of cell and tissue within the body. The serum proteome has
been shown to contain information that directly reflects pathophysiological ... Cited by 128 - Related articles - BL Direct - All 6 versions
S Havelund, A Plum, U Ribel, I Jonassen, A … - Pharmaceutical research, 2004 - Springer The peptide hormone, insulin, is produced and stored in pancreatic beta-cells.
An adaptation of beta-cell insulin pro- duction is the assembly of insulin
molecules at high concen- tration in the presence of zinc ions into ... Cited by 94 - Related articles - BL Direct - All 3 versions
- ►mcponline.org TD Veenstra, TP Conrads, BL Hood, AM … - Molecular & Cellular Proteomics, 2005 - ASBMB Proteomics has brought with it the hope of identifying novel biomarkers for
diseases such as cancer. This hope is built on the ability of proteomic
technologies, such as mass spectrometry (MS), to identify hundreds of ... Cited by 94 - Related articles - BL Direct - All 4 versions
JT Feng, YK Liu, HY Song, Z Dai, LX Qin, MR … - Proteomics, 2005 - interscience.wiley.com Hepatocellular carcinoma (HCC) is the third leading cause of cancer mortality
worldwide and ranks second in China. The prognosis of HCC remains dismal mainly
because of its late diagnosis, especially in patients with coexisting ... Cited by 87 - Related articles - All 4 versions
P Kurtzhals - International Journal of Obesity, 2004 - nature.com The suboptimal nature of the absorption profiles of human insulin formulations
following subcutaneous administration has prompted the development of insulin
analogues better suited for therapeutic use in diabetes mellitus. A ... Cited by 64 - Related articles - BL Direct - All 5 versions
P Home, P Kurtzhals - Expert Opin. Pharmacother., 2006 - Informa Pharma Science Insulin detemir (Levemir®, Novo Nordisk) is a novel, biologically engineered
analogue of human insulin that has been successfully developed for clinical use
in diabetes as a basal insulin. Its unique mechanism of prolongation of ... Cited by 58 - Related articles - BL Direct - All 5 versions
GI Uwaifo, RE Ratner - Endocrinology and metabolism clinics of North America, 2005 - Elsevier Since the discovery of insulin by Banting and Best in the early 20th century,
the clinical management of diabetes has undergone significant changes. The last
decade has been associated with an explosion in therapeutic options for ... Cited by 38 - Related articles - All 3 versions
M Hamilton-Wessler, M Ader, MK Dea, D … - Diabetes, 2002 - Am Diabetes Assoc A defect in transcapillary transport of insulin in skeletal muscle and adipose
tissue has been proposed to play a role in the insulin resistance that leads to
type 2 diabetes, yet the mechanism of insulin transfer across the capillary ... Cited by 26 - Related articles - BL Direct - All 4 versions
FJ Gómez-Pérez, JA Rull - Archives of medical research, 2005 - Elsevier In normal humans, blood glucose and insulin are maintained within a narrow range
despite wide variations in physical activity and dietary intake. At present,
reproducing this pattern is an impossible task in type 1 diabetes and ... Cited by 25 - Related articles - All 12 versions
MA Vincent, LH Clerk, S Rattigan, MG Clark, … - Clinical and Experimental Pharmacology and …, 2005 - interscience.wiley.com It is also possible that your web browser is not configured or not able to
display style sheets. In this case, although the visual presentation will be
degraded, the site should continue to be functional. We recommend using the ... Cited by 25 - Related articles - All 5 versions
