C Hernández-Sánchez, A Mansilla, J Enrique, … - The EMBO Journal, 2003 - pubmedcentral.nih.gov Proinsulin is expressed prior to development of the pancreas and promotes cell
survival. Here we study the mechanism affecting the translation efficiency of a
specific embryonic proinsulin mRNA. This transcript shares the coding ... Cited by 34 - Related articles - BL Direct - All 8 versions
- ►shouxi.net CW Hay, K Docherty - Diabetes, 2006 - Am Diabetes Assoc DNA sequences that regulate expression of the insulin gene are located within a
region spanning ∼400 bp that flank the transcription start site. This region,
the insulin promoter, contains a number of cis-acting elements that bind ... Cited by 31 - Related articles - BL Direct - All 9 versions
A Santana, R Ensenat-Waser, MI Arribas, JA … - Journal of Cellular and Molecular Medicine, 2006 - curemosladiabetes.com Type 1 diabetes is characterized by the selective destruction of pancreatic
ß-cells caused by an autoimmune attack. Type 2 diabetes is a more complex
pathology which, in addition to ß-cell loss caused by apoptotic programs, ... Cited by 25 - Related articles - View as HTML - BL Direct - All 5 versions
A Mansilla, C López-Sánchez, EJ de la Rosa, … - EMBO reports, 2005 - pubmedcentral.nih.gov Proinsulin gene expression regulation and function during early embryonic
development differ remarkably from those found in postnatal organisms. The
embryonic proinsulin protein content decreased from gastrulation to ... Cited by 21 - Related articles - BL Direct - All 4 versions
C Hernandez-Sanchez, A Mansilla, EJ de la … - Diabetologia, 2006 - Springer Abstract In postnatal organisms, insulin is well known as an essential anabolic
hormone responsible for maintaining glucose homeostasis. Its biosynthesis by the
pancreatic beta cell has been considered a model of tissue-specific gene ... Cited by 15 - Related articles - BL Direct - All 3 versions
P Boya, EJ de la Rosa - BIRTH DEFECTS RESEARCH PART C EMBRYO …, 2005 - interscience.wiley.com Programmed cell death is a relevant process in the physiology and pathology of
the nervous system. Neuronal cell death during development is well
characterized, and studies of this process have provided valuable ... Cited by 14 - Related articles - BL Direct - All 3 versions
AI Valenciano, S Corrochano, F de Pablo, P de … - Journal of neurochemistry, 2006 - assets0.pubget.com Abstract Programmed cell death is an essential, highly regulated pro- cess in
neural development. Although the role of insulin-like growth factor I in
supporting the survival of neural cells has been well characterized, ... Cited by 9 - Related articles - View as HTML - BL Direct - All 6 versions
TA Hughes, HJM Brady - Journal of Biological Chemistry, 2005 - ASBMB Axin2 is a negative regulator of Wnt/β-catenin signaling with roles in early
development and tumor suppression. We find that axin2 expression is regulated at
both transcriptional and translational levels. The gene allows ... Cited by 8 - Related articles - All 6 versions
