- ►unam.mx [PDF] DE Cummings, MW Schwartz - Annual Review of Medicine, 2003 - Annual Reviews Obesity has become a leading public health concern. Over 1 billion people are
now overweight or obese, and the prevalence of these conditions is rising
rapidly. Remarkable new insights into the mechanisms that control body ... Cited by 192 - Related articles - BL Direct - All 7 versions
MW Schwartz, SC Woods, RJ Seeley, GS … - Diabetes, 2003 - Am Diabetes Assoc We describe a model of energy homeostasis to better understand neuronal pathways
that control energy balance and their regulation by hormonal signals such as
insulin and leptin. Catabolic neuronal pathways are those that both reduce ... Cited by 187 - Related articles - BL Direct - All 16 versions
- ►ebmonline.org MM Berglund, PA Hipskind, DR Gehlert - Experimental Biology and Medicine, 2003 - SEBM The three peptides pancreatic polypeptide (PP), peptide YY (PYY), and
neuropeptide Y (NPY) share a similar structure known as the PP-fold. There are
four known human G-protein coupled receptors for the PP-fold peptides, ... Cited by 114 - Related articles - BL Direct - All 4 versions
G Williams, JA Harrold, DJ Cutler - Proceedings of the Nutrition Society, 2007 - Cambridge Univ Press Proceedings of the Nutrition Society (2000), 59, 385–396 ... Abbreviations:
AGRP, agouti gene-related peptide; ARC, arcuate nucleus; CNS, central nervous
system; DMH, dorsomedial hypothalamic nucleus; LHA, lateral hypothalamic ... Cited by 106 - Related articles - BL Direct - All 2 versions
- ►fasebj.org A INUI, A ASAKAWA, CY BOWERS, G … - The FASEB Journal, 2004 - FASEB Recent progress in the field of energy homeostasis was triggered by the
discovery of adipocyte hormone leptin and revealed a complex regulatory
neuroendocrine network. A late addition is the novel stomach hormone ... Cited by 105 - Related articles - BL Direct - All 5 versions
- ►rockefeller.edu [PDF] SF Leibowitz, KE Wortley - Peptides, 2004 - Elsevier Energy balance is maintained via a homeostatic system involving both the brain
and the periphery. A key component of this system is the hypothalamus. Over the
past two decades, major advances have been made in identifying an ... Cited by 104 - Related articles - All 7 versions
SP Kalra, PS Kalra - Endocrine, 2003 - Springer Received April 14, 2003; Accepted April 14, 2003. Author to whom all
correspondence and reprint requests should be addressed: Satya P. Kalra, PhD,
Department of Neuroscience, University of Florida McKnight Brain Institute, ... Cited by 61 - Related articles - BL Direct - All 6 versions
- ►diabetesjournals.org C Namkoong, MS Kim, PG Jang, SM Han, HS … - Diabetes, 2005 - Am Diabetes Assoc AMP-activated protein kinase (AMPK) acts as a cellular energy sensor, being
activated during states of low energy charge. Hypothalamic AMPK activity is
altered by hormonal and metabolic signals and mediates the feeding ... Cited by 36 - Related articles - All 7 versions
TM Mizuno, KA Kelley, GM Pasinetti, JL … - Diabetes, 2003 - Am Diabetes Assoc Hypothalamic proopiomelanocortin (POMC) gene expression is reduced in many forms
of obesity and diabetes, particularly in those attributable to deficiencies in
leptin or its receptor. To assess the functional significance of POMC in ... Cited by 36 - Related articles - BL Direct - All 5 versions
- ►physiology.org G Segal-Lieberman, DJ Trombly, V Juthani, X … - American Journal of Physiology- Endocrinology And …, 2003 - Am Physiological Soc Neuropeptide Y (NPY) is an orexigenic (appetite-stimulating) peptide that plays
an important role in regulating energy balance. When administered directly into
the central nervous system, animals exhibit an immediate increase in ... Cited by 35 - Related articles - BL Direct - All 4 versions
