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Scholar Results 1 - 10 of about 25 citing Blaak: The fate of [U-13C] palmitate extracted by skeletal muscle in subjects with type 2.... (0.14 sec) 

Triacylglycerol accumulation in human obesity and type 2 diabetes is associated with …

- fasebj.org [PDF] 
A Bonen, ML Parolin, GR Steinberg, J Calles … - The FASEB Journal, 2004 - FASEB
Page 1. The FASEB Journal express article 10.1096/fj.03-1065fje. Published online
May 7, 2004. Triacylglycerol accumulation in human obesity and type 2 ...
Cited by 132 - Related articles - BL Direct - All 7 versions

Dynamic changes in fat oxidation in human primary myocytes mirror metabolic …

- nih.gov
B Ukropcova, M McNeil, O Sereda, L de Jonge … - Journal of Clinical Investigation, 2005 - Am Soc Clin Investig
Metabolic flexibility of skeletal muscle, that is, the preference for fat
oxidation (FOx) during fasting and for carbohydrate oxidation in response to
insulin, is decreased during insulin resistance. The aim of this study was ...
Cited by 50 - Related articles - BL Direct - All 12 versions

Normal insulin sensitivity and IMCL content in overweight humans are associated with higher …

- physiology.org
G Perseghin, P Scifo, M Danna, A Battezzati, … - American Journal of Physiology- Endocrinology And …, 2002 - Am Physiological Soc
Intramyocellular lipid (IMCL) storage is considered a local marker of whole body
insulin resistance; because increments of body weight are supposed to impair
insulin sensitivity, this study was designed to assess IMCL content, lipid ...
Cited by 40 - Related articles - BL Direct - All 3 versions

The glucose–fatty acid cycle: a physiological perspective


K Frayn - Biochemical Society Transactions, 2003 - bst.portlandpress.com
Glucose and fatty acids are the major fuels for mammalian metabolism and it is
clearly essential that mechanisms exist for mutual co-ordination of their
utilization. The glucose–fatty acid cycle, as it was proposed in 1963, ...
Cited by 38 - Related articles - Cached - BL Direct - All 9 versions

Diabetes: mellitus or lipidus?


E Shafrir, I Raz - Diabetologia, 2003 - Springer
Since ancient times the search for causes of diabetes was related to the
sweetness of urine and other body fluids. In England, Thomas Willis
(1621–1675) was among the first to taste the urine of diabetic patients ...
Cited by 35 - Related articles - BL Direct - All 3 versions

Basic disturbances in skeletal muscle fatty acid metabolism in obesity and type 2 diabetes …


EE Blaak - Proceedings of the Nutrition Society, 2007 - Cambridge Univ Press
The present article addresses the hypothesis that disturbances in skeletal
muscle fatty acid handling in abdominal obesity and type 2 diabetes mellitus may
play a role in the aetiology of increased adipose tissue stores, increased ...
Cited by 31 - Related articles - BL Direct - All 5 versions

Determinants of intramyocellular triglyceride turnover: implications for insulin sensitivity

- physiology.org
C Moro, S Bajpeyi, SR Smith - American Journal of Physiology- Endocrinology And …, 2008 - Am Physiological Soc
Increased intramyocellular triglyceride (IMTG) content is found in both
insulin-sensitive endurance-trained subjects and insulin-resistant obese/type 2
diabetic subjects. A high turnover rate of the IMTG pool in athletes is ...
Cited by 23 - Related articles - BL Direct - All 6 versions

Impaired fatty acid metabolism in type 2 diabetic skeletal muscle cells is reversed by PPAR …

- physiology.org
BS Cha, TP Ciaraldi, KS Park, L Carter, SR … - American Journal of Physiology- Endocrinology And …, 2005 - Am Physiological Soc
The impact of type 2 diabetes on the ability of muscle to accumulate and dispose
of fatty acids and triglycerides was evaluated in cultured muscle cells from
nondiabetic (ND) and type 2 diabetic (T2D) subjects. In the presence of 5 ...
Cited by 24 - Related articles - BL Direct - All 4 versions

Metabolic fluxes in skeletal muscle in relation to obesity and insulin resistance


EE Blaak - Best Practice & Research Clinical Endocrinology & …, 2005 - Elsevier
The present article addresses the hypothesis that inefficient skeletal muscle
lipid utilization may relate to the development of obesity and insulin
resistance. In practice, there is evidence of impaired muscle fatty acid ...
Cited by 16 - Related articles - All 16 versions

Glucose clearance is higher in arm than leg muscle in type 2 diabetes


DB Olsen, M Sacchetti, F Dela, T Ploug, B … - The Journal of Physiology, 2005 - Physiological Soc
Insulin-mediated glucose clearance (GC) is diminished in type 2 diabetes.
Skeletal muscle has been estimated to account for essentially all of the
impairment. Such estimations were based on leg muscle and extrapolated to ...
Cited by 12 - Related articles - All 9 versions


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