- ►endojournals.org JH Lee, JL Chan, N Yiannakouris, M … - Journal of Clinical Endocrinology & Metabolism, 2003 - Endocrine Soc Resistin is a novel adipocyte-secreted hormone proposed to link obesity with
diabetes. Studies in mice have revealed conflicting data however, and the
physiological role of circulating resistin in humans remains unknown. We ... Cited by 263 - Related articles - BL Direct - All 6 versions
YC Chagnon, T Rankinen, EE Snyder, SJ … - Obesity, 2003 - nature.com This is the ninth update of the human obesity gene map, incorporating published
results through October 2002 and continuing the previous format. Evidence from
single-gene mutation obesity cases, Mendelian disorders exhibiting obesity ... Cited by 225 - Related articles - BL Direct - All 6 versions
CM Steppan, MA Lazar - Journal of Internal Medicine, 2004 - interscience.wiley.com Obesity and noninsulin-dependent diabetes mellitus are globally epidemic.
Insulin resistance is a major contributor to the pathogenesis of type II
diabetes and plays a role in numerous other metabolic disorders including ... Cited by 208 - Related articles - BL Direct - All 4 versions
SR Smith, F Bai, C Charbonneau, L … - Diabetes, 2003 - Am Diabetes Assoc Insulin resistance is a component of type 2 diabetes and often precedes
pancreatic β-cell failure. Contributing factors include obesity and a central
pattern of fat accumulation with a strong genetic component. The adipocyte ... Cited by 113 - Related articles - BL Direct - All 6 versions
- ►nih.gov JK Kim, RE Gimeno, T Higashimori, HJ Kim, H … - Journal of Clinical Investigation, 2004 - Am Soc Clin Investig 1 Department of Internal Medicine, Yale University School of Medicine, New
Haven, Connecticut, USA. 2 Millennium Pharmaceuticals Inc., Cambridge,
Massachusetts, USA. 3 Whitehead Institute for Biomedical Research, ... Cited by 112 - Related articles - BL Direct - All 11 versions
- ►upenn.edu [PDF] RR Banerjee, MA Lazar - Journal of Molecular Medicine, 2003 - Springer Insulin resistance, the inability of target tissues to re- spond normally to
insulin, is central to the pathophysiol- ogy of type 2 diabetes [1], but its
molecular basis re- mains poorly understood. Classically, the explanation ... Cited by 93 - Related articles - BL Direct - All 4 versions
- ►eje-online.org [PDF] O Ukkola - European journal of endocrinology, 2002 - EFES The objective of this review is to summarize the current evidence of a novel
adipocytokine, resistin. Resistin is a novel peptide hormone that belongs to a
family of tissue-specific resistin-like molecules originally named for its ... Cited by 85 - Related articles - BL Direct - All 13 versions
M Urbanek, Y Du, K Silander, FS Collins, CM … - Diabetes, 2003 - Am Diabetes Assoc Polycystic ovary syndrome (PCOS) is a leading cause of anovulatory infertility
and affects ∼4–7% of reproductive age women in the US It is characterized by
hyperandrogenemia and chronic anovulation and is associated with insulin ... Cited by 69 - Related articles - BL Direct - All 4 versions
- ►endojournals.org A Pizzuti, A Argiolas, R Di Paola, R Baratta, A … - Journal of Clinical Endocrinology & Metabolism, 2002 - Endocrine Soc Resistin is overexpressed in human adipose tissue of obese individuals and is
likely to modulate insulin sensitivity. Resistin is, therefore, a candidate gene
for insulin resistance. We searched for polymorphisms in the resistin gene ... Cited by 63 - Related articles - BL Direct - All 4 versions
H Parikh, L Groop - Reviews in Endocrine & Metabolic Disorders, 2004 - Springer About 150 million people suffer from type 2 diabetes in the world today and it
has been predicted that this num- ber will be doubled within 15 years [1]. It is
no longer a disease of the elderly, age at onset has decreased with the ... Cited by 62 - Related articles - BL Direct - All 3 versions