O Tschritter, A Fritsche, F Shirkavand, F … - Diabetes Care, 2003 - Am Diabetes Assoc RESULTS—In the biphasic group, the NGT-to-IGT ratio was slightly higher
(173/20 vs. 209/40, P = 0.08) and the male-to-female ratio was lower (60/133 vs.
120/129, P = 0.0003). Subjects with a biphasic shape had significantly ... Cited by 22 - Related articles - BL Direct - All 6 versions
RM Van Dam, B Hoebee, JC Seidell, MM … - Diabetic Medicine, 2004 - interscience.wiley.com Aims The insulin receptor substrate-1 (IRS-1) gene is among the most frequently
studied candidate genes for Type 2 diabetes, but findings have been
inconsistent. This may have been due to generally small study sizes, or to ... Cited by 21 - Related articles - BL Direct - All 4 versions
- ►diabetesjournals.org LM t Hart, TW van Haeften, JM Dekker, M Bot … - Diabetes, 2002 - Am Diabetes Assoc An association between type 2 diabetes and genetic variation in the KIR6.2 gene
has been reported in several populations. Based on in vitro studies with cell
lines expressing the Glu 23 Lys (E23K) mutation, it was recently suggested ... Cited by 19 - Related articles - BL Direct - All 6 versions
- ►nursing2008.com M Urbanek, RS Spielman - Current Opinion in Endocrinology, Diabetes and …, 2002 - journals.lww.com The genetic analysis of polycystic ovary syndrome (PCOS) presents the typical
problems associated with the inheritance of a common, complex disorder. Despite
evidence for substantial familial aggregation of PCOS the mode of ... Cited by 14 - Related articles - BL Direct - All 2 versions
- ►unimaas.nl [PDF] A Jellema, RP Mensink, D Kromhout, WHM … - Atherosclerosis, 2003 - Elsevier The relationship between the Gly972Arg polymorphism in the insulin receptor
substrate-1 (IRS-1) gene and metabolic risk markers is not clear, possibly due
to small sample sizes. Modification by body mass index (BMI) has also been ... Cited by 9 - Related articles - All 11 versions
K Tamada, XP Wang, FC Brunicardi - World journal of surgery, 2005 - Springer Abstract. During the last decade significant advances in gene therapy have made
it possible to treat various pancreatic disorders in both animal models and in
humans. For example, insulin gene delivery to non-b-cell tissues has been ... Cited by 10 - Related articles - All 3 versions
MF Shehata - Cardiovascular diabetology, 2008 - cardiab.com Despite the marked advances in research on insulin resistance (IR) in humans and
animal models of insulin resistance, the mechanisms underlying high salt-induced
insulin resistance remain unclear. Insulin resistance is a multifactorial ... Cited by 5 - Related articles - Cached - All 8 versions
EC Tok, D Ertunc, O Bilgin, EM Erdal, M … - American journal of obstetrics and gynecology, 2006 - Elsevier Insulin receptor substrate-1 (IRS-1) expression and tyrosine phosphorylation is
decreased during pregnancy. Pregnancy may be a suitable condition to detect any
abnormalities related to IRS-1 polymorphisms. Therefore, we aimed to ... Cited by 4 - Related articles - All 10 versions
S Baudler, W Krone, JC Brüning - Best Practice & Research Clinical Endocrinology & …, 2003 - Elsevier To understand the mechanism of insulin signalling and insulin resistance in the
development of type 2 diabetes, it is necessary to elucidate the role of insulin
and related signal molecules in normal cellular development and functions. ... Cited by 2 - Related articles - All 3 versions