- ►ahajournals.org SC Benson, HA Pershadsingh, CI Ho, A … - Hypertension, 2004 - Am Heart Assoc The metabolic syndrome is a common precursor of cardiovascular disease and type
2 diabetes that is characterized by the clustering of insulin resistance,
dyslipidemia, and increased blood pressure. In humans, mutations in the ... Cited by 428 - Related articles - BL Direct - All 10 versions
S Engeli, P Schling, K Gorzelniak, M … - International Journal of Biochemistry and Cell Biology, 2003 - Elsevier Overfeeding of rodents leads to increased local formation of angiotensin II due
to increased secretion of angiotensinogen from adipocytes. Whereas angiotensin
II promotes adipocyte growth and preadipocyte recruitment, increased ... Cited by 170 - Related articles - All 4 versions
- ►diabetesjournals.org J Tonelli, W Li, P Kishore, UB Pajvani, E … - Diabetes, 2004 - Am Diabetes Assoc Whereas thiazolidinediones (TZDs) are known to rapidly improve insulin action in
animals, short durations of TZD therapy have never been studied in humans. Among
the many known actions of TZDs, increased circulating levels of the high ... Cited by 142 - Related articles - BL Direct - All 5 versions
V Fonseca - The American journal of medicine, 2003 - Elsevier Treatment of diabetes mellitus with medications, including insulin,
sulfonylureas, and thiazolidinediones (TZDs), often leads to weight gain through
a variety of mechanisms. Weight gain can have adverse consequences for ... Cited by 107 - Related articles - All 8 versions
- ►diabetesjournals.org M Laplante, H Sell, KL MacNaul, D Richard, … - Diabetes, 2003 - Am Diabetes Assoc This study sought to determine whether the adipose depot−specific
(subcutaneous [SF] vs. visceral [VF]) action of peroxisome
proliferator−activated receptor-γ (PPAR-γ) agonists on fat deposition ... Cited by 77 - Related articles - BL Direct - All 5 versions
- ►physiology.org AS Lihn, B Richelsen, SB Pedersen, SB … - American Journal of Physiology- Endocrinology And …, 2003 - Am Physiological Soc Human immunodeficiency virus (HIV)-associated lipodystrophy syndrome (HALS) is a
side effect of highly active antiretroviral therapy of HIV-infected patients;
however, the mechanism of the lipodystrophy and insulin resistance seen in ... Cited by 73 - Related articles - BL Direct - All 3 versions
JK Kim, JJ Fillmore, O Gavrilova, L Chao, T … - Diabetes, 2003 - Am Diabetes Assoc To determine the role of adipocytes and the tissue-specific nature in the
insulin sensitizing action of rosiglitazone, we examined the effects of 3 weeks
of rosiglitazone treatment on insulin signaling and action during ... Cited by 60 - Related articles - BL Direct - All 5 versions
HR Kast-Woelbern, SL Dana, RM Cesario, L … - Journal of Biological Chemistry, 2004 - ASBMB Insulin-induced gene 1 (INSIG-1) is a key regulator in the processing of the
sterol regulatory element-binding proteins (SREBPs). We demonstrated that
Insig-1 is regulated by peroxisome proliferator-activated receptor (PPAR ) ... Cited by 42 - Related articles - BL Direct - All 5 versions
A Hsiao, DS Worrall, JM Olefsky, S … - BIOINFORMATICS-OXFORD-, 2004 - Oxford Univ Press 1 Department of Bioengineering, UC San Diego, La Jolla, CA 92093, USA, 2
Department of Medicine, UC San Diego, La Jolla, CA 92093, USA, 3 Department of
Chemistry and Biochemistry, UC San Diego, La Jolla, CA 92093, USA Cited by 39 - Related articles - BL Direct - All 6 versions
T Allen, F Zhang, SA Moodie, LE Clemens, A … - Diabetes, 2006 - Am Diabetes Assoc Halofenate has been shown previously to lower triglycerides in dyslipidemic
subjects. In addition, significant decreases in fasting plasma glucose were
observed but only in type 2 diabetic patients. We hypothesized that ... Cited by 37 - Related articles - BL Direct - All 9 versions
