S Boudina, ED Abel - Circulation, 2007 - Am Heart Assoc The prevalence of diabetes mellitus is growing rapidly. It is estimated that
globally the number of adults affected with diabetes will increase from 135
million in 1995 to 300 million by 2025. 1 Patients with diabetes mellitus ... Cited by 136 - Related articles - All 5 versions
- ►ahajournals.org M Scheuermann-Freestone, PL Madsen, D … - Circulation, 2003 - Am Heart Assoc Methods and Results— We studied 21 patients with type 2 diabetes with no
evidence of coronary artery disease or impaired cardiac function, as determined
by echocardiography, and 15 age-, sex-, and body mass index-matched control ... Cited by 131 - Related articles - All 7 versions
MA Gonzalez, AP Selwyn - The American journal of medicine, 2003 - Elsevier Endothelial dysfunction may be evaluated by means of invasive techniques, such
as coronary artery reactivity to acetylcholine, or noninvasive techniques, such
as brachial artery ultrasonography. Loss of endothelium-dependent ... Cited by 125 - Related articles - All 9 versions
IG Poornima, P Parikh, RP Shannon - Circulation research, 2006 - Am Heart Assoc Although diabetes is recognized as a potent and prevalent risk factor for
ischemic heart disease, less is known as to whether diabetes causes an altered
cardiac phenotype independent of coronary atherosclerosis. Left ventricular ... Cited by 114 - Related articles - All 7 versions
- ►ahajournals.org EL Schiffrin, F Amiri, K Benkirane, M Iglarz, … - Hypertension, 2003 - Am Heart Assoc Peroxisome proliferator-activated receptors (PPAR) are nuclear receptors acting
as transcription factors on numerous target genes after heterodimerization with
the retinoid X receptor. PPAR- and PPAR- may be activated by different ... Cited by 109 - Related articles - BL Direct - All 8 versions
- ►diabetesjournals.org E Aasum, AD Hafstad, DL Severson, TS … - Diabetes, 2003 - Am Diabetes Assoc Glucose and palmitate metabolism and contractile function were measured with ex
vivo perfused working hearts from control (db/+) and diabetic (db/db) female
mice at 6, 10–12, and 16–18 weeks of age. Palmitate oxidation was ... Cited by 102 - Related articles - BL Direct - All 4 versions
PK Mazumder, BT O'Neill, MW Roberts, J … - Diabetes, 2004 - Am Diabetes Assoc Diabetes alters cardiac substrate metabolism. The cardiac phenotype in
insulin-resistant states has not been comprehensively characterized. The goal of
these studies was to determine whether the hearts of leptin-deficient ... Cited by 99 - Related articles - BL Direct - All 6 versions
A Sivarajah, PK Chatterjee, NSA Patel, Z … - Am J Nephrol, 2003 - content.karger.com Background/Aims: Recent evidence indicates that peroxisome-proliferator
activated receptor (PPAR) agonists protect against ischemia/reperfusion (I/R)
injury. Here we investigate the effects of the PPAR- agonists, ... Cited by 90 - Related articles - BL Direct - All 6 versions
- ►physiology.org EL Schiffrin - American Journal of Physiology- Heart and Circulatory …, 2005 - Am Physiological Soc Peroxisome proliferator-activated receptors (PPARs) are nuclear receptors that
heterodimerize with the retinoid X receptor and then modulate the function of
many target genes. Three PPARs are known: , / , and . The better known are ... Cited by 85 - Related articles - All 7 versions
