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Scholar Results 1 - 10 of about 118 citing Desco: Xanthine oxidase is involved in free radical production in type 1 diabetes. (0.18 sec) 

Diabetes and vascular disease: pathophysiology, clinical consequences, and medical therapy …


MA Creager, TF Luscher, F Cosentino, JA … - Circulation, 2003 - Am Heart Assoc
Diabetes mellitus affects approximately 100 million persons worldwide. 1 Five to
ten percent have type 1 (formerly known as insulin-dependent) and 90% to 95%
have type 2 (non–insulin-dependent) diabetes mellitus. It is likely that ...
Cited by 394 - Related articles - BL Direct - All 6 versions

Biomarkers of diabetes-associated oxidative stress and antioxidant status in young diabetic …


P Martín-Gallán, A Carrascosa, M Gussinyé, … - Free Radical Biology and Medicine, 2003 - Elsevier
The aims of the study were to ascertain the potential role of oxidative stress
in the onset of disease-related pathophysiological complications in young type 1
diabetes patients. Indicative parameters of lipoperoxidation, protein ...
Cited by 117 - Related articles - All 4 versions

Novel inhibitors of advanced glycation endproducts

- morelife.org [PDF] 
S Rahbar, JL Figarola - Archives of Biochemistry and Biophysics, 2003 - Elsevier
A number of natural or synthetic compounds as AGE inhibitors have been proposed,
discovered or currently being advanced by others and us. We have identified two
new classes of aromatic compounds; aryl- (and heterocyclic) ureido and aryl ...
Cited by 109 - Related articles - BL Direct - All 10 versions

Modulation of oxidant and antioxidant enzyme expression and function in vascular cells

- ahajournals.org
S Wassmann, K Wassmann, G Nickenig - Hypertension, 2004 - Am Heart Assoc
Pathological conditions that predispose to cardiovascular events, such as
hypertension, hypercholesterolemia, and diabetes, are associated with oxidative
stress. These observations and further data derived from a plethora of ...
Cited by 101 - Related articles - BL Direct - All 7 versions

Use of allopurinol in slowing the progression of renal disease through its ability to lower …


YP Siu, KT Leung, MKH Tong, TH Kwan - American Journal of Kidney Diseases, 2006 - Elsevier
Background: Hyperuricemia is associated strongly with the development of
hypertension, renal disease, and progression. Allopurinol decreases serum uric
acid levels by inhibiting the enzyme xanthine oxidase. We hypothesized that ...
Cited by 93 - Related articles - All 3 versions

A review on the role of antioxidants in the management of diabetes and its complications


R Rahimi, S Nikfar, B Larijani, M Abdollahi - Biomedicine & Pharmacotherapy, 2005 - Elsevier
Diabetes is a prevalent systemic disease affecting a significant proportion of
the population worldwide. The effects of diabetes are devastating and well
documented. There is increasing evidence that in certain pathologic states, ...
Cited by 92 - Related articles - All 5 versions

Therapeutic effects of xanthine oxidase inhibitors: renaissance half a century after the …

- aspetjournals.org
P Pacher, A Nivorozhkin, C Szabo - Pharmacological reviews, 2006 - ASPET
The prototypical xanthine oxidase (XO) inhibitor allopurinol, has been the
cornerstone of the clinical management of gout and conditions associated with
hyperuricemia for several decades. More recent data indicate that XO also ...
Cited by 91 - Related articles - BL Direct - All 10 versions

Evidence for contribution of vascular NAD (P) H oxidase to increased oxidative stress in …


T Sonta, T Inoguchi, H Tsubouchi, N … - Free Radical Biology and Medicine, 2004 - Elsevier
It is well established that oxidative stress is enhanced in diabetes. However,
the major in vivo source of oxidative stress is not clear. Here we show that
vascular NAD(P)H oxidase may be a major source of oxidative stress in ...
Cited by 84 - Related articles - All 5 versions

Aldose reductase inhibitor fidarestat prevents retinal oxidative stress and vascular …

- pubget.com [PDF] 
IG Obrosova, AG Minchenko, R Vasupuram, L … - Diabetes, 2003 - Am Diabetes Assoc
The study addressed the role for aldose reductase (AR) in 1) retinal oxidative
stress and vascular endothelial growth factor (VEGF) overexpression in early
diabetes, and 2) high glucose-induced oxidative stress in retinal ...
Cited by 83 - Related articles - BL Direct - All 5 versions

The role of oxidative stress in diabetic vascular and neural disease


MA Yorek - Free radical research, 2003 - informahealthcare.com
This review will focus on the impact of hyperglycemia- induced oxidative stress
in the development of diabetes- induced vascular and neural dysfunction.
Oxidative stress occurs when the balance between the production of ...
Cited by 74 - Related articles - BL Direct - All 8 versions


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