- ►ahajournals.org J Kim, M Montagnani, KK Koh, MJ Quon - Circulation, 2006 - Am Heart Assoc Endothelial dysfunction contributes to cardiovascular diseases, including hypertension,
atherosclerosis, and coronary artery disease, which are also characterized by insulin
resistance. Insulin resistance is a hallmark of metabolic disorders, including type 2 ... Cited by 322 - Related articles - All 9 versions
- ►physiology.org MG Clark, MG Wallis, EJ Barrett, MA … - American Journal of …, 2003 - Am Physiological Soc The vascular system controls the delivery of nutrients and hormones to muscle, and a number
of hormones may act to regulate muscle metabolism and contractile performance by modulating
blood flow to and within muscle. This review examines evidence that insulin has major ... Cited by 146 - Related articles - BL Direct - All 4 versions
MA Vincent, LH Clerk, JR Lindner, AL Klibanov, MG … - Diabetes, 2004 - Am Diabetes Assoc Insulin increases glucose disposal into muscle. In addition, in vivo insulin elicits distinct nitric
oxide synthase-dependent vascular responses to increase total skeletal muscle blood flow and
to recruit muscle capillaries (by relaxing resistance and terminal arterioles, respectively). ... Cited by 101 - Related articles - BL Direct - All 5 versions
- ►endojournals.org R Muniyappa, M Montagnani, KK Koh, MJ Quon - Endocrine reviews, 2007 - Endocrine Soc Insulin has important vascular actions to stimulate production of nitric oxide from
endothelium. This leads to capillary recruitment, vasodilation, increased blood flow, and subsequent
augmentation of glucose disposal in classical insulin target tissues (e.g., skeletal muscle). ... Cited by 101 - Related articles - BL Direct - All 5 versions
- ►ahajournals.org RT de Jongh, EH Serne, RG IJzerman, G de Vries, … - Circulation, 2004 - Am Heart Assoc From the Department of Medicine (RTJ, EHS, RGIJ, GV, CDAS), VU University Medical
Center, Amsterdam, Netherlands, and Institute for Cardiovascular Research, Vrije Universiteit
(RTJ, EHS, RGIJ, CDAS), Amsterdam, Netherlands. ... Correspondence to Prof Dr Coen ... Cited by 98 - Related articles - BL Direct - All 5 versions
- ►physiology.org MA Vincent, EJ Barrett, JR Lindner, MG … - American Journal of …, 2003 - Am Physiological Soc We examined the effects of inhibiting nitric oxide synthase with N -nitro-L-arginine-methyl ester
(L-NAME) on total hindlimb blood flow, muscle microvascular recruitment, and hindlimb glucose
uptake during euglycemic hyperinsulinemia in vivo in the rat. We used two independent ... Cited by 89 - Related articles - BL Direct - All 3 versions
MA Vincent, M Montagnani, MJ Quon - Current Diabetes Reports, 2003 - Springer Insulin has important vascular actions that regulate blood flow, in addition to its classical actions
to coordinate glu- cose homeostasis. Insulin-stimulated production of nitric oxide in vascular
endothelium results in capillary recruit- ment and vasodilation that diverts and increases ... Cited by 90 - Related articles - BL Direct - All 2 versions
RT de Jongh, EH Serné, RG IJzerman, G de Vries, … - Diabetes, 2004 - Am Diabetes Assoc To test the hypothesis that free fatty acids (FFAs) modulate microvascular function and that this
contributes to obesity-associated insulin resistance, hypertension, and microangiopathy, we
examined the effects of both FFA elevation in lean women and FFA lowering in obese ... Cited by 72 - Related articles - BL Direct - All 4 versions
D An, B Rodrigues - American Journal of Physiology- Heart and …, 2006 - Am Physiological Soc In patients with diabetes, an increased risk of symptomatic heart failure usually develops in the
presence of hypertension or ischemic heart disease. However, a predisposition to heart failure
might also reflect the effects of underlying abnormalities in diastolic function that can ... Cited by 67 - Related articles - BL Direct - All 5 versions
