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Scholar Results 1 - 10 of about 82 citing Mohr: Caspase activation in retinas of diabetic and galactosemic mice and diabetic patients. (0.10 sec) 

Poly (ADP-ribose) polymerase is involved in the development of diabetic retinopathy via …


L Zheng, C Szabó, TS Kern - Diabetes, 2004 - Am Diabetes Assoc
The current study investigated the role of poly(ADP-ribose) polymerase (PARP) in
the development of diabetic retinopathy. Activity of PARP was increased in whole
retina and in endothelial cells and pericytes of diabetic rats. ...
Cited by 98 - Related articles - BL Direct - All 5 versions

Death of retinal neurons in streptozotocin-induced diabetic mice

- iovs.org
PM Martin, P Roon, TK Van Ells, V Ganapathy … - Investigative ophthalmology & visual science, 2004 - ARVO
RESULTS. Morphometric analysis of retinal cross sections of mice that had been
diabetic 14 weeks showed 20% to 25% fewer cells in the ganglion cell layer
compared with age-matched control mice. There was a modest, but ...
Cited by 83 - Related articles - BL Direct - All 3 versions

Vascular endothelial growth factor and diabetic retinopathy: role of oxidative stress


RB Caldwell, M Bartoli, MA Behzadian, AEB … - Current drug targets, 2005 - ingentaconnect.com
Ruth B. Caldwell 1,2,4, * , Manuela Bartoli 1,5 , M. Ali Behzadian 1,3 , Azza EB
El-Remessy 1,3 , Mohamed ... Al-Shabrawey 1 , Daniel H. Platt 1,3 , Gregory I.
Liou 4 and R. William Caldwell 3 ... 1 Vascular Biology Center, 2 ...
Cited by 67 - Related articles - All 2 versions

The Ins2Akita mouse as a model of early retinal complications in diabetes

- iovs.org
AJ Barber, DA Antonetti, TS Kern, CEN … - Investigative ophthalmology & visual science, 2005 - ARVO
RESULTS. The mean blood glucose of Ins2 Akita mice was significantly elevated,
whereas the body weight at death was reduced compared with that of control
animals. Compared with sibling control mice, the Ins2 Akita mice had ...
Cited by 60 - Related articles - All 4 versions

Diabetes-induced mitochondrial dysfunction in the retina

- iovs.org
RA Kowluru, SN Abbas - Investigative ophthalmology & visual science, 2003 - ARVO
METHODS. Mitochondria and cytosol fractions were prepared from retina of rats
with streptozotocin-induced diabetes and from the isolated retinal endothelial
cells and pericytes incubated in 5 or 20 mM glucose medium for up to 10 ...
Cited by 52 - Related articles - BL Direct - All 4 versions

Oxidative stress inactivates VEGF survival signaling in retinal endothelial cells via PI 3- …

- biologists.org
AB El-Remessy, M Bartoli, DH Platt, D Fulton, … - Journal of cell science, 2005 - jcs.biologists.org
In diabetic retinopathy, endothelial cell apoptosis is paradoxically increased
despite upregulation of the potent pro-survival factor VEGF. We tested the
hypothesis that elevated glucose levels disrupt VEGF's pro-survival ...
Cited by 51 - Related articles - All 8 versions

Nuclear translocation of glyceraldehyde-3-phosphate dehydrogenase: a role in high glucose- …

- iovs.org
LL Kusner, VP Sarthy, S Mohr - Investigative ophthalmology & visual science, 2004 - ARVO
PURPOSE. A recent study demonstrated that retinal Müller cells undergo
hyperglycemia-induced apoptosis in vitro. Translocation of
glyceraldehyde-3-phosphate dehydrogenase (GAPDH) from the cytosol to the ...
Cited by 41 - Related articles - BL Direct - All 5 versions

Caspase activation in an experimental model of retinal detachment

- iovs.org
DN Zacks, V Hanninen, M Pantcheva, E Ezra, … - Investigative ophthalmology & visual science, 2003 - ARVO
METHODS. Retinal detachments were created in Brown Norway rats by injecting 10%
hyaluronic acid into the subretinal space using a transvitreous approach. Light
microscopy and terminal dUTP-biotin nick end-labeling (TUNEL) was performed ...
Cited by 41 - Related articles - BL Direct - All 4 versions

Vascular damage in a mouse model of diabetic retinopathy: relation to neuronal and glial …

- iovs.org
RA Feit-Leichman, R Kinouchi, M Takeda, Z … - Investigative ophthalmology & visual science, 2005 - ARVO
RESULTS. There was transient induction of cell apoptosis and caspase-3
activation in retinal neurons of C57Bl/6 mice within days of diabetes induction.
Glial fibrillary acidic protein (GFAP), a marker of glial activation, ...
Cited by 36 - Related articles - BL Direct - All 5 versions

Comparative therapy evaluation of intravitreal bevacizumab and triamcinolone acetonide on …


M Shimura, T Nakazawa, K Yasuda, T Shiono, … - American journal of ophthalmology, 2008 - Elsevier
Before the injection, foveal thickness and VA were 522.3 ± 91.3 μm and 0.64 ±
0.28 μm in the triamcinolone-injected eye, and 527.6 ± 78.8 μm and 0.61 ±
0.18 μm in the bevacizumab-injected eye, respectively; there was no ...
Cited by 36 - Related articles - All 34 versions


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