N Bouck - Trends in molecular medicine, 2002 - Elsevier Sight-threatening eye diseases can be caused and exacerbated by the aberrant
growth of new blood vessels. Recent work indicates that this neovascularization
not only is a response to a rise in the local concentration of molecules ... Cited by 107 - Related articles - All 12 versions
- ►nih.gov H Liu, JG Ren, WL Cooper, CE Hawkins, MR … - Proceedings of the National Academy of Sciences of …, 2004 - National Acad Sciences Vascular permeability plays a key role in a wide array of life-threatening and
sight-threatening diseases. Vascular endothelial growth factor can increase
vascular permeability. Using a model system for nonproliferative diabetic ... Cited by 72 - Related articles - BL Direct - All 16 versions
JL Wilkinson-Berka - Current pharmaceutical design, 2004 - ingentaconnect.com Abstract: The pathogenetic agents involved in the development of diabetic
retinopathy are diverse. In the setting of hyperglycaemia and retinal hypoxia a
number of vasoactive factors may interact to promote pathology in a variety ... Cited by 66 - Related articles - BL Direct - All 5 versions
- ►amjpathol.org P Baluk, CG Lee, H Link, E Ator, A Haskell, … - American Journal of Pathology, 2004 - ASIP Angiogenesis and vascular remodeling occurs in many inflammatory diseases,
including asthma. In this study, we determined the time course and reversibility
of the angiogenesis and vascular remodeling produced by vascular ... Cited by 53 - Related articles - BL Direct - All 6 versions
- ►iovs.org K Ohno-Matsui, T Uetama, T Yoshida, M Hayano … - Investigative ophthalmology & visual science, 2003 - ARVO METHODS. C57Bl/6 (MMP-2 +/+ and -9 +/+ ), MMP-2–deficient (MMP-2 -/- ), and
MMP-9–deficient (MMP-9 -/- ) mice were used. After oxygen-induced retinopathy
was induced in the mice, their eyes were rapidly removed and frozen in ... Cited by 43 - Related articles - BL Direct - All 4 versions
- ►endocrinology-journals.org SX Zhang, JJ Wang, G Gao, K Parke, J Ma - Journal of molecular endocrinology, 2006 - Soc Endocrinology It has been shown that the balance between vascular endothelial growth factor
(VEGF), a major angiogenic stimulator, and pigment epithelium-derived factor
(PEDF), a potent angiogenic inhibitor, is critical for the regulation of ... Cited by 37 - Related articles - BL Direct - All 3 versions
M Koulu, S Movafagh, J Tuohimaa, U Jaakkola, … - Annals of Medicine, 2004 - informahealthcare.com BACKGROUND: Neuropeptide Y is a sympathetic neuro- transmitter, a potent
endothelium-derived angiogenic factor and a vascular mitogen. We have studied
the role of the functional leucine7 to proline7 polymorphism of the signal ... Cited by 33 - Related articles - BL Direct - All 7 versions
L Notari, A Miller, A Martinez, J Amaral, M … - Investigative ophthalmology & visual science, 2005 - iovs.org.p.angrylapdog.com METHODS. Mouse models for retinopathy of prematurity (ROP) were used. Cultured
monkey RPE cells were exposed to low oxygen and chemical hypoxia mimetics. PEDF
and VEGF mRNA levels in RPE were determined by RT-PCR. MMPs were assessed ... Cited by 32 - Related articles - BL Direct - All 4 versions
- ►amjpathol.org SX Zhang, J Ma, J Sima, Y Chen, MS Hu, A … - American Journal of Pathology, 2005 - ASIP The breakdown of the blood-retina barrier (BRB) is a common feature of diabetic
retinopathy. The purpose of the present study is to determine whether there are
genetic differences in susceptibility to the breakdown of the BRB in ... Cited by 30 - Related articles - All 6 versions
SX Zhang, J Sima, C Shao, J Fant, Y Chen, B … - Diabetologia, 2004 - Springer Aims/hypothesis. Retinal vascular leakage is an early pathological feature in
diabetic retinopathy and can lead to macular oedema and loss of vision.
Previously we have shown that plasminogen kringle 5 (K5), an angiogenic ... Cited by 30 - Related articles - BL Direct - All 5 versions
