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Scholar Results 1 - 10 of about 87 citing Jensen: Early differential defects of insulin secretion and action in 19-year-old Caucasian.... (0.10 sec) 

Low birthweight is associated with specific changes in muscle insulin-signalling protein …

- nodak.edu [PDF] 
SE Ozanne, CB Jensen, KJ Tingey, H … - Diabetologia, 2005 - Springer
Abstract Aims/hypothesis: People with low birthweight have an increased risk of
developing type 2 diabetes mel- litus in adulthood. The mechanistic basis of
this pheno- menon is not known. Here we investigate the effect of early ...
Cited by 85 - Related articles - All 4 versions

Mechanisms by which poor early growth programs type-2 diabetes, obesity and the …

- ucilmsa.org [PDF] 
DS Fernandez-Twinn, SE Ozanne - Physiology & behavior, 2006 - Elsevier
Fetal programming is gaining momentum as a highly documented phenomenon which
links poor early growth to adult disease. It is backed up by large cohorts in
epidemiological studies worldwide and has been tested in various animal ...
Cited by 76 - Related articles - All 5 versions

Birth weight and subsequent cholesterol levels: exploration of the" fetal origins" hypothesis

- angrylapdog.com
R Huxley, CG Owen, PH Whincup, DG Cook, S … - JAMA: The Journal of the American Medical …, 2004 - jama.ama-assn.org.p.angrylapdog.com
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Cited by 61 - Related articles - Cached - BL Direct - All 8 versions

Effect of maternal feed restriction during pregnancy on glucose tolerance in the adult guinea …

- physiology.org
KL Kind, PM Clifton, PA Grant, PC Owens, A … - … Journal of Physiology- Regulatory, Integrative and …, 2003 - Am Physiological Soc
Maternal nutrient restriction and impaired fetal growth are associated with
postnatal insulin resistance, hyperinsulinemia, and glucose intolerance in
humans but not consistently in other species, such as the rat or sheep. We ...
Cited by 49 - Related articles - BL Direct - All 7 versions

Type 2 diabetes mellitus in youth: the complete picture to date


N Gungor, T Hannon, I Libman, F Bacha, S … - The Pediatric Clinics of North America, 2005 - Elsevier
Type 2 diabetes mellitus (T2DM) historically was considered a disease of adults,
with autoimmune type 1 diabetes mellitus (T1DM) accounting for almost all cases
of pediatric diabetes. T2DM was recognized as a disease of the pediatric ...
Cited by 43 - Related articles - All 16 versions

Intrauterine growth restriction—etiology and consequences: what do we know about the …


Z Ergaz, M Avgil, A Ornoy - Reproductive Toxicology, 2005 - Elsevier
Embryonic and fetal growth depend on genetic and environmental factors, and the
process is the result of the interaction between these factors. About 7–9% of
live-born infants have a birth weight below normal (below the 10th ...
Cited by 39 - Related articles - All 4 versions

Pharmacologic approaches to the prevention of type 2 diabetes in high risk pediatric …


M Freemark - Journal of Clinical Endocrinology & Metabolism, 2003 - Endocrine Soc
The past generation has witnessed a surge in the number of children,
adolescents, and young adults with type 2 diabetes (1, 2, 3). In most cases the
illness begins with excess weight gain, insulin resistance, and ...
Cited by 38 - Related articles - BL Direct - All 5 versions

Prenatal depression effects on the fetus and newborn: a review

- ahealthymind.org [PDF] 
T Field, M Diego, M Hernandez-Reif - Infant Behavior and Development, 2006 - Elsevier
A review of research on prenatal depression effects on the fetus and newborn
suggests that they experience prenatal, perinatal and postnatal complications.
Fetal activity is elevated, prenatal growth is delayed, and prematurity and ...
Cited by 38 - Related articles - All 4 versions

Normal insulin-stimulated endothelial function and impaired insulin-stimulated muscle …

- endojournals.org
TS Hermann, C Rask-Madsen, N Ihlemann, H … - Journal of Clinical Endocrinology & Metabolism, 2003 - Endocrine Soc
Low birth weight has been linked to insulin resistance and cardiovascular
disease. We hypothesized that insulin sensitivity of both muscle and vascular
tissues were impaired in young men with low birth weight. Blood flow was ...
Cited by 36 - Related articles - BL Direct - All 4 versions

Developmental origins of adult metabolic disease: concepts and controversies


R Simmons - Trends in Endocrinology & Metabolism, 2005 - Elsevier
The 'thrifty phenotype' hypothesis proposes that the fetus adapts to an adverse
intrauterine milieu by optimizing the use of a reduced nutrient supply to ensure
survival. However, favoring the development of some organs over that of ...
Cited by 37 - Related articles - All 8 versions


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