- ►diabetesjournals.org K Bouzakri, M Roques, P Gual, S Espinosa, F … - Diabetes, 2003 - Am Diabetes Assoc To understand better the defects in the proximal steps of insulin signaling
during type 2 diabetes, we used differentiated human skeletal muscle cells in
primary culture. When compared with cells from control subjects, myotubes ... Cited by 98 - Related articles - BL Direct - All 4 versions
- ►physiology.org A Corbould, YB Kim, JF Youngren, C Pender, … - American Journal of Physiology- Endocrinology And …, 2005 - Am Physiological Soc Insulin resistance in polycystic ovary syndrome (PCOS) is due to a postbinding
defect in signaling that persists in cultured skin fibroblasts and is associated
with constitutive serine phosphorylation of the insulin receptor (IR). ... Cited by 62 - Related articles - All 3 versions
- ►physiology.org HM Wilmsen, TP Ciaraldi, L Carter, N … - American Journal of Physiology- Endocrinology And …, 2003 - Am Physiological Soc We examined the regulation of free fatty acid (FFA, palmitate) uptake into
skeletal muscle cells of nondiabetic and type 2 diabetic subjects. Palmitate
uptake included a protein-mediated component that was inhibited by ... Cited by 58 - Related articles - BL Direct - All 4 versions
K Højlund, P Stæhr, BF Hansen, KA Green, … - Diabetes, 2003 - Am Diabetes Assoc In type 2 diabetes, insulin activation of muscle glycogen synthase (GS) is
impaired. This defect plays a major role for the development of insulin
resistance and hyperglycemia. In animal muscle, insulin activates GS by ... Cited by 58 - Related articles - BL Direct - All 4 versions
- ►diabetesjournals.org M Gaster, AC Rustan, V Aas, H Beck-Nielsen - Diabetes, 2004 - Am Diabetes Assoc Insulin resistance in skeletal muscle in vivo is associated with reduced lipid
oxidation and lipid accumulation. It is still uncertain whether changes in lipid
metabolism represent an adaptive compensation at the cellular level or a ... Cited by 52 - Related articles - BL Direct - All 4 versions
L Al-Khalili, M Forsgren, K Kannisto, JR … - Diabetologia, 2005 - Springer Abstract Aims/hypothesis: The aim of this study was to determine the effect of
several antidiabetic agents on in- sulin-stimulated glycogen synthesis, as well
as on mRNA expression. Methods: Cultured primary human skeletal myo- tubes ... Cited by 38 - Related articles - All 5 versions
- ►diabetesjournals.org ET Kase, AJ Wensaas, V Aas, K Højlund, K … - Diabetes, 2005 - Am Diabetes Assoc Liver X receptors (LXRs) are important regulators of cholesterol and lipid
metabolism and are also involved in glucose metabolism. However, the functional
role of LXRs in human skeletal muscle is at present unknown. This study ... Cited by 37 - Related articles - All 6 versions
H Beck-Nielsen, A Vaag, P Poulsen, M Gaster - Best Practice & Research Clinical Endocrinology & …, 2003 - Elsevier Based on our investigations in first-degree relatives, in twins in general, and
in monozygotic twins discordant for type 2 diabetes, we have studied the
inheritance of glucose intolerance, insulin resistance and insulin ... Cited by 34 - Related articles - All 6 versions
BM Abdallah, H Beck-Nielsen, M Gaster - Eur J Clin Invest, 2005 - interscience.wiley.com Background Alterations in glucocorticoid hormone metabolism in skeletal muscle
have been suggested to contribute to the pathogenesis of the metabolic syndrome.
Circulating glucocorticoids consist of inactive cortisone and active ... Cited by 26 - Related articles - BL Direct - All 3 versions
