E Tomas, TS Tsao, AK Saha, HE Murrey, … - Proceedings of the …, 2002 - National Acad Sciences The hormone ACRP30, also referred to as adiponectin and adipo Q (1), is exclusively secreted by
differentiated adipocytes (2). It circulates in serum as three distinct oligomers: trimer, hexamer,
and an even higher molecular weight ... Cited by 512 - Related articles - BL Direct - All 10 versions
- ►psychiatryonline.org CL Raison, AH Miller - American Journal of Psychiatry, 2003 - Am Psychiatric Assoc OBJECTIVE: Previous theories have emphasized the role of excessive glucocorticoid activity in the
pathology of chronic stress. Nevertheless, insufficient glucocorticoid signaling (resulting from
decreased hormone bioavailability ... Cited by 245 - Related articles - BL Direct - All 7 versions
H Ruan, HF Lodish - Cytokine and Growth Factor Reviews, 2003 - Elsevier Insulin resistance is a fundamental defect that precedes the development of the full insulin
resistance syndrome as well as β cell failure and type 2 diabetes. Tumor necrosis factor-α
(TNF-α), a paracrine/autocrine ... Cited by 240 - Related articles - All 10 versions
- ►jbc.org TS Tsao, HE Murrey, C Hug, DH Lee, HF Lodish - Journal of Biological …, 2002 - ASBMB Adipocyte complement-related protein of 30 kDa (Acrp30)/adiponectin is an adipocyte-derived hormone
that affects lipid and glucose metabolism in muscle and liver, but its physical and biochemical
properties are poorly ... Cited by 190 - Related articles - BL Direct - All 5 versions
I Juhan-Vague, MC Alessi, A Mavri, PE … - Journal of Thrombosis …, 2003 - interscience.wiley.com Summary. Elevated plasma plasminogen activator inhibitor-1 (PAI-1) level is a core feature of
insulin-resistance syndrome (IRS). Atherothrombotic complications in IRS are partly attributed to
impaired fibrinolysis caused by ... Cited by 170 - Related articles - BL Direct - All 3 versions
- ►nih.gov S Acharyya, KJ Ladner, LL Nelsen, J … - Journal of Clinical …, 2004 - Am Soc Clin Investig Cachexia is a syndrome characterized by wasting of skeletal muscle and contributes to nearly
one-third of all cancer deaths. Cytokines and tumor factors mediate wasting by suppressing muscle
gene products, but exactly which ... Cited by 166 - Related articles - BL Direct - All 12 versions
H Ruan, PDG Miles, CM Ladd, K Ross, TR Golub, JM … - Diabetes, 2002 - Am Diabetes Assoc Despite extensive studies implicating tumor necrosis factor (TNF)-α as a contributing cause of
insulin resistance, the mechanism(s) by which TNF-α alters energy metabolism in vivo and the tissue
specificity of TNF-α action are ... Cited by 157 - Related articles - BL Direct - All 6 versions
- ►jlr.org FB Kraemer, WJ Shen - The Journal of Lipid Research, 2002 - ASBMB Hormone-sensitive lipase (HSL) is an intracellular neutral lipase that is capable of hydrolyzing
triacylglycerols, diacylglycerols, monoacylglycerols, and cholesteryl esters, as well as other lipid
and water soluble substrates. HSL ... Cited by 116 - Related articles - BL Direct - All 5 versions
- ►ahajournals.org YH Yu, HN Ginsberg - Circulation research, 2005 - Am Heart Assoc For many years adipose tissue was viewed as the site where excess energy was stored, in the form of
triglycerides (TGs), and where that energy, when needed elsewhere in the body, was released in the
form of fatty acids (FAs). ... Cited by 108 - Related articles - All 7 versions
PA Permana, C Menge, PD Reaven - Biochemical and biophysical research …, 2006 - Elsevier Macrophage infiltration into adipose tissue increases with obesity, a condition associated with
low-grade inflammation and insulin resistance. We investigated the direct effects of
macrophage-secreted factors on ... Cited by 106 - Related articles - All 5 versions
