- ►nih.gov [PDF] V Sanna, A Di Giacomo, A La Cava, RI … - Journal of Clinical Investigation, 2003 - Am Soc Clin Investig In the work presented here, we explored the influence of leptin on the kinetics
of experimental autoimmune encephalomyelitis (EAE) onset, in the EAE-associated
inflammatory anorexia, and in the development of pathogenic T cell ... Cited by 145 - Related articles - BL Direct - All 10 versions
M Otero, R Lago, F Lago, FF Casanueva, C … - FEBS letters, 2005 - Elsevier Leptin is 16 kDa adipokine that links nutritional status with neuroendocrine and
immune functions. Initially thought to be a satiety factor that regulates body
weight by inhibiting food intake and stimulating energy expenditure, leptin ... Cited by 145 - Related articles - All 5 versions
TJ Guzik, D Mangalat, R Korbut - Journal Of Physiology and Pharmacology, 2006 - jpp.krakow.pl Obesity and obesity related diseases are a major public health problem. Recent
studies have shown that fat tissue is not a simple energy storage organ, but
exerts important endocrine and immune functions. These are achieved ... Cited by 130 - Related articles - Cached - BL Direct - All 6 versions
V Sanchez-Margalet, C Martin-Romero, J … - Clinical and experimental immunology, 2003 - pubmedcentral.nih.gov Leptin is a an adipocyte-secreted hormone that regulates weight centrally.
However, the leptin receptor is expressed not only in the central nervous
system, but also in peripheral tissues, such as haematopoietic and immune ... Cited by 123 - Related articles - BL Direct - All 6 versions
A La Cava, C Alviggi, G Matarese - Journal of Molecular Medicine, 2004 - Springer Page 1. J Mol Med (2004) 82:4–11 DOI 10.1007/s00109-003-0492-1 REVIEW Antonio
La Cava · Carlo Alviggi · Giuseppe Matarese Unraveling ... Cited by 89 - Related articles - BL Direct - All 4 versions
- ►shouxi.net MY Donath, JA Ehses, K Maedler, DM … - Diabetes, 2005 - Am Diabetes Assoc A decrease in the number of functional insulin-producing β-cells contributes to
the pathophysiology of type 2 diabetes. Opinions diverge regarding the relative
contribution of a decrease in β-cell mass versus an intrinsic defect in ... Cited by 85 - Related articles - BL Direct - All 6 versions
- ►diabetesjournals.org [PDF] A Imagawa, T Funahashi, T Nakamura, M … - Diabetes Care, 2002 - Am Diabetes Assoc In type 2 diabetes, coronary artery dis- ease (CAD), the major cause of mortal-
ity, is often diagnosed late because of silent myocardial ischemia (MI) (1).
Asymptomatic type 2 diabetic patients, particularly those with additional ... Cited by 90 - Related articles - BL Direct - All 5 versions
F Peelman, W Waelput, H Iserentant, D … - Progress in Lipid Research, 2004 - Elsevier Leptin was originally discovered as an adipocyte-derived hormone involved in the
central control of body weight and energy homeostasis. It is now clear that
leptin is a pleiotropic cytokine, with activities on many peripheral cell ... Cited by 77 - Related articles - All 2 versions
P Stattin, R Palmqvist, S Söderberg, C … - Oncology reports - ncbi.nlm.nih.gov Obesity is associated with an increased risk of colorectal cancer. Circulating
levels of leptin are high in obesity and strongly correlated to levels of
insulin. Leptin stimulates growth of colon cancer cells. In a nested case- ... Cited by 71 - Related articles - BL Direct - All 4 versions
G Matarese, A La Cava - Trends in immunology, 2004 - Elsevier Increasing experimental evidence indicates that several factors that influence
metabolism also play a role in the regulation of immune responses. Dissection of
the interface connecting the metabolic and immune systems has recently ... Cited by 68 - Related articles - All 6 versions
