V Mathews, PT Hanson, E Ford, J Fujita, KS Polonsky, … - Diabetes, 2004 - Am Diabetes Assoc Endothelial progenitor cells (EPCs) are detectable in the blood and bone marrow throughout
life. These cells contribute to new blood vessel formation (neovascularization) in physiological
states such as wound healing and in pathological states such as tumor angiogenesis. We ... Cited by 117 - Related articles - BL Direct - All 4 versions
AK Cardozo, P Proost, C Gysemans, MC Chen, C … - Diabetologia, 2003 - Springer Aims/hypothesis. Cytokines and chemokines are im- portant mediators of immune responses
due to their ability to recruit and activate leukocytes. Using micro- array analysis we observed
that rat beta cells exposed to IL-1β and IFN-γ have increased mRNA levels of chemokines ... Cited by 86 - Related articles - BL Direct - All 5 versions
N Zhang, A Richter, J Suriawinata, S Harbaran, J … - Diabetes, 2004 - Am Diabetes Assoc Successful islet transplantation depends on the infusion of sufficiently large quantities of
islets, of which only ∼30% become stably engrafted. Rapid and adequate revascularization
of transplanted islets is important for islet survival and function. Delayed and insufficient ... Cited by 80 - Related articles - BL Direct - All 6 versions
L Jansson, PO Carlsson - Diabetologia, 2002 - Springer Endogenous pancreatic islets have a dense glomeru- lar-like angioarchitecture, which ensures
an optimal delivery of oxygen and nutrients to the islet cells, pro- vides signals from other cells
in the body and disposes secreted hormones. Transplantation of isolated islets means ... Cited by 80 - Related articles - BL Direct - All 5 versions
- ►endojournals.org PO Carlsson, F Palm, G Mattsson - Journal of Clinical Endocrinology & …, 2002 - Endocrine Soc Pancreatic islets are avascular immediately after transplantation. Although the islets are rapidly
revascularized, it is uncertain whether the revascularization produces an adequate oxygenation
of the transplanted islet tissue. We measured pO 2 , blood flow and vascular density in ... Cited by 61 - Related articles - BL Direct - All 4 versions
- ►endojournals.org J Gromada, I Franklin, CB Wollheim - Endocrine reviews, 2007 - Endocrine Soc Glucagon, a hormone secreted from the -cells of the endocrine pancreas, is critical for blood
glucose homeostasis. It is the major counterpart to insulin and is released during hypoglycemia
to induce hepatic glucose output. The control of glucagon secretion is multifactorial and ... Cited by 61 - Related articles - BL Direct - All 4 versions
Y Lai, D Schneider, A Kidszun, I Hauck- … - Transplantation, 2005 - journals.lww.com Transplantation. Wolters Kluwer Health | Lippincott Williams & Wilkins. All Issues. ... Cited by 47 - Related articles - All 4 versions
- ►diabetesjournals.org D Nyqvist, M Köhler, H Wahlstedt, PO Berggren - Diabetes, 2005 - Am Diabetes Assoc Pancreatic islet transplantation has emerged as a therapy for type 1 diabetes and is today performed
using both freshly isolated and cultured islets. Islet blood vessels are disrupted during islet
isolation; therefore, proper revascularization of the transplanted islets is of great ... Cited by 43 - Related articles - BL Direct - All 6 versions
- ►diabetesjournals.org N Zhang, D Su, S Qu, T Tse, R Bottino, AN … - Diabetes, 2006 - Am Diabetes Assoc Successful islet transplantation depends on the infusion of sufficiently large quantities of
islets, but only a fraction of transplanted islets can survive and become engrafted, and yet the
underlying mechanism remains unclear. In this study, we examined the effect of sirolimus, ... Cited by 42 - Related articles - BL Direct - All 7 versions
- ►diabetesjournals.org JL Contreras, C Eckstein, CA Smyth, G Bilbao, M … - Diabetes, 2004 - Am Diabetes Assoc Clinical studies indicate that significant loss of functional islet mass occurs in the peritransplant
period. Islets are injured as a result of detrimental effects of brain death, pancreas
preservation, islet isolation, hypoxia, hyperglycemia, and immune-mediated events. In ... Cited by 40 - Related articles - BL Direct - All 4 versions
