- ►pnas.org AY Savinov, A Tcherepanov, EA Green, RA … - Proceedings of the National Academy of Sciences, 2003 - National Acad Sciences Fas (Tnfrsf6, Apo-1, CD95) is a death receptor involved in apoptosis induced in
many cell types. Fas have been shown to be expressed by insulin-producing beta
cells in mice and humans. However, the importance of Fas in the development ... Cited by 59 - Related articles - BL Direct - All 9 versions
- ►fasebj.org [PDF] AM Joussen, V Poulaki, N Mitsiades, W Cai, I … - The FASEB Journal, 2002 - FASEB The FASEB Journal express article 10.1096/fj.02-0157fje. Published online
November 15, 2002. ... Suppression of Fas-FasL-induced endothelial cell
apoptosis ... Antonia M. Joussen, *,†,§,** Vassiliki Poulaki, *,§,** ... Cited by 58 - Related articles - BL Direct - All 4 versions
O Micheau - ett, 2003 - Informa Pharma Science Cellular FLIP (c-FLIP), also known as FLICE-inhibitory protein, has been iden-
tified as an inhibitor of apoptosis triggered by engagement of death recep- tors
(DRs) such as Fas or TRAIL (TNF-related apoptosis-inducing ligand). c-FLIP ... Cited by 41 - Related articles - BL Direct - All 4 versions
H Hui, F Dotta, UD Mario, R Perfetti - Journal of cellular physiology, 2004 - interscience.wiley.com The homeostatic control of beta-cell mass in normal and pathological conditions
is based on the balance of proliferation, differentiation, and death of the
insulin-secreting cells. A considerable body of evidence, accumulated ... Cited by 42 - Related articles - BL Direct - All 4 versions
- ►rupress.org I Apostolou, Z Hao, K Rajewsky, H von … - Journal of Experimental Medicine, 2003 - jem.rupress.org In type 1 diabetes, autoimmune T cells cause destruction of pancreatic ß cells
by largely unknown mechanism. Previous analyses have shown that ß cell
destruction is delayed but can occur in perforin-deficient nonobese ... Cited by 35 - Related articles - BL Direct - All 5 versions
- ►jimmunol.org J Allison, HE Thomas, T Catterall, TWH Kay, A … - The Journal of Immunology, 2005 - Am Assoc Immnol In type 1 diabetes, many effector mechanisms damage the cell, a key one being
perforin/granzyme B production by CD8 + T cells. The death receptor pathway has
also been implicated in cell death, and we have therefore generated NOD ... Cited by 24 - Related articles - All 7 versions
- ►jimmunol.org R Darwiche, MMW Chong, P Santamaria, HE … - The Journal of Immunology, 2003 - Am Assoc Immnol Fas (CD95) is a potential mechanism of pancreatic cell death in type 1 diabetes.
cells do not constitutively express Fas but it is induced by cytokines. The
hypothesis of this study is that Fas expression should be measurable on ... Cited by 24 - Related articles - BL Direct - All 4 versions
M Pearl-Yafe, A Kaminitz, ES Yolcu, I Yaniv, … - Current pharmaceutical design, 2007 - ingentaconnect.com Abstract: Abundant information is available on the involvement of various
cellular and molecular mechanisms in cell apoptosis. The experimental evidence
is controversial and difficult to reconcile, and the mechanisms of evasion ... Cited by 17 - Related articles - BL Direct - All 3 versions
MS Lee, I Chang, S Kim - Molecular Genetics and Metabolism, 2004 - Elsevier While it is generally agreed that apoptosis of pancreatic β-cells is the most
important and final step in the progression of type 1 diabetes without which
clinical diabetes does not develop, it has not been elucidated which ... Cited by 16 - Related articles - All 3 versions
S Chakrabarty, M Nagata, H Yasuda, L Wen, … - Clinical and Experimental Immunology, 2003 - pubmedcentral.nih.gov CD30/CD30L is a member of tumour necrosis factor (TNF) receptor/TNF superfamily
and has been implicated in immune-regulation. A genetic study has also suggested
a possible implication of CD30 in spontaneous autoimmune diabetes in NOD ... Cited by 17 - Related articles - BL Direct - All 6 versions
