- ►endojournals.org J Eeckhoute, E Moerman, T Bouckenooghe, B … - Endocrinology, 2003 - Endocrine Soc The nuclear receptor hepatocyte nuclear factor (HNF) 4 is involved in a
transcriptional network and plays an important role in pancreatic ß-cells.
Mutations in the HNF4 gene are correlated with maturity-onset diabetes of ... Cited by 58 - Related articles - BL Direct - All 3 versions
K Yoneda, T Furukawa, YJ Zheng, T Momoi, I … - Journal of Biological Chemistry, 2004 - ASBMB Epidermolysis bullosa simplex (EBS) is a blistering cutaneous disease featuring
protein aggregates. Here we investigate the molecular mechanisms linking protein
aggregates to cell death in a cellular model of EBS in which HaCaT ... Cited by 27 - Related articles - BL Direct - All 5 versions
SG Gray, P De Meyts - Diabetes/Metabolism Reviews - interscience.wiley.com Globally, diabetes (and, in particular, type 2 diabetes) represents a major
challenge to world health. Currently in the United States, the costs of treating
diabetes and its associated complications exceed $100 billion annually, and ... Cited by 26 - Related articles - BL Direct - All 3 versions
- ►nih.gov J Eeckhoute, P Formstecher, B Laine - Nucleic acids research, 2004 - Oxford Univ Press Hepatocyte Nuclear Factor 1 (HNF1 ) and Hepatocyte Nuclear Factor 4 (HNF4 ) are
two liver-enriched transcription factors coexpressed in specific tissues where
they play a crucial role through their involvement in a complex ... Cited by 19 - Related articles - BL Direct - All 10 versions
- ►jimmunol.org H Schjerven, P Brandtzaeg, FE Johansen - The Journal of Immunology, 2003 - Am Assoc Immnol Secretory IgA and IgM, which protect the mucosal surfaces, are generated by
selective transport of locally produced polymeric (p)Igs through the epithelial
barrier by the pIgR. The expression of this receptor, and hence the ... Cited by 14 - Related articles - BL Direct - All 4 versions
- ►eje-online.org ME Cerf - European Journal of Endocrinology, 2006 - EFES In humans, mutations in specific genes lead to the various forms of
maturity-onset diabetes of the young (MODY). MODY is a subtype of diabetes
characterized by autosomal dominant inheritance, non-ketotic diabetes ... Cited by 12 - Related articles - BL Direct - All 7 versions
- ►uky.edu [PDF] KA Kim, K Kang, YI Chi, I Chang, MK Lee, … - Diabetologia, 2003 - Springer Aims/hypothesis. After screening 16 Korean families with early onset Type 2
diabetes in search for hepato- cyte nuclear factor (HNF)-1α gene mutation, we
iden- tified a novel missense mutation (R263L) associated with MODY ... Cited by 10 - Related articles - BL Direct - All 6 versions
F Arenas, I Hervias, M Úriz, R Joplin, J Prieto … - The Journal of Clinical Investigation, 2008 - pubmedcentral.nih.gov Primary biliary cirrhosis (PBC) is a cholestatic disease associated with
autoimmune phenomena and alterations in both biliary bicarbonate excretion and
expression of the bicarbonate carrier AE2. The bile acid ursodeoxycholic ... Cited by 10 - Related articles - BL Direct - All 8 versions
SK PARK, VH HAASE, RS JOHNSON - International journal of oncology, 2007 - cat.inist.fr von Hippel Lindau tumor suppressor regulates hepatic glucose metabolism by controlling
expression of glucose transporter 2 and glucose 6-phosphatase. ... Cited by 8 - Related articles - BL Direct - All 3 versions
- ►nih.gov M Yu, J Wang, W Li, YZ Yuan, CY Li, XH … - Nucleic Acids Research, 2007 - Oxford Univ Press Hepatocyte nuclear factor (HNF)-1 is one of the liver-enriched transcription
factors involved in many tissue-specific expressions of hepatic genes. The
molecular mechanisms for determining HNF1 -mediated transactivation have ... Cited by 7 - Related articles - BL Direct - All 7 versions
