V Schulla, E Renström, R Feil, S Feil, I … - The EMBO Journal, 2003 - pubmedcentral.nih.gov Insulin is secreted from pancreatic β cells in response to an elevation of
cytoplasmic Ca 2+ resulting from enhanced Ca 2+ influx through voltage-gated Ca
2+ channels. Mouse β cells express several types of Ca 2+ channel (L-, R- ... Cited by 75 - Related articles - All 3 versions
YM Leung, Y Kang, X Gao, F Xia, H Xie, L … - Journal of Biological Chemistry, 2003 - ASBMB Voltage-gated K + (Kv) 2.1 is the dominant Kv channel that controls membrane
repolarization in rat islet -cells and downstream insulin exocytosis. We
recently showed that exocytotic SNARE protein SNAP-25 directly binds and ... Cited by 68 - Related articles - BL Direct - All 4 versions
- ►endojournals.org DC Thurmond, C Gonelle-Gispert, M Furukawa … - Molecular Endocrinology, 2003 - Endocrine Soc The actin monomer sequestering agent latrunculin B depolymerized ß-cell
cortical actin, which resulted in increased glucose-stimulated insulin secretion
in both cultured MIN6 ß-cells and isolated rat islet cells. In perifused ... Cited by 57 - Related articles - BL Direct - All 3 versions
- ►endojournals.org PE MacDonald, G Wang, S Tsuk, C Dodo, Y … - Molecular Endocrinology, 2002 - Endocrine Soc Insulin secretion is initiated by ionic events involving membrane depolarization
and Ca 2+ entry, whereas exocytic SNARE (soluble N-ethylmaleimide-sensitive
factor attachment protein receptor) proteins mediate exocytosis itself. In ... Cited by 48 - Related articles - BL Direct - All 3 versions
D Mears - Journal of Membrane Biology, 2004 - Springer Page 1. Regulation of Insulin Secretion in Islets of Langerhans by Ca 2+
Channels David Mears Department of Anatomy, Physiology & ... Cited by 41 - Related articles - BL Direct - All 5 versions
- ►jbc.org BS Finlin, AL Mosley, SM Crump, RN Correll, … - Journal of Biological Chemistry, 2005 - ASBMB Voltage-dependent calcium (Ca 2+ ) channels are involved in many specialized
cellular functions and are controlled by a diversity of intracellular signals.
Recently, members of the RGK family of small GTPases (Rem, Rem2, Rad, ... Cited by 38 - Related articles - BL Direct - All 5 versions
- ►physiology.org AG Garcia… - Physiological reviews, 2006 - Am Physiological Soc At a given cytosolic domain of a chromaffin cell, the rate and amplitude of the
Ca 2+ concentration ([Ca 2+ ] c ) depends on at least four efficient regulatory
systems: 1) plasmalemmal calcium channels, 2) endoplasmic reticulum, 3) ... Cited by 34 - Related articles - BL Direct - All 4 versions
- ►endojournals.org SN Yang, PO Berggren - Endocrine reviews, 2006 - Endocrine Soc Voltage-gated calcium (Ca V ) channels are ubiquitously expressed in various
cell types throughout the body. In principle, the molecular identity,
biophysical profile, and pharmacological property of Ca V channels are ... Cited by 34 - Related articles - BL Direct - All 6 versions
- ►mendeley.com [PDF] DJ Müller, TA Klempan, V De Luca, T Sicard … - Neuroscience letters, 2005 - Elsevier The synaptosomal-associated protein of 25 kDa (SNAP-25) is an essential
component of the core complex that mediates presynaptic vesicle trafficking.
Thus, SNAP-25 is directly involved in the release of neurotransmitters. ... Cited by 35 - Related articles - All 5 versions
- ►physiology.org SN Yang, PO Berggren - American Journal of Physiology- Endocrinology And …, 2005 - Am Physiological Soc The -cell is equipped with at least six voltage-gated Ca 2+ (Ca V ) channel 1
-subunits designated Ca V 1.2, Ca V 1.3, Ca V 2.1, Ca V 2.2, Ca V 2.3, and Ca V
3.1. These principal subunits, together with certain auxiliary subunits, ... Cited by 31 - Related articles - All 3 versions
