- ►diabetesjournals.org DJ Drucker - Diabetes Care, 2003 - Am Diabetes Assoc RESULTS—Glucagon-like peptide 1 (GLP-1) and glucose-dependent insulinotropic
peptide (GIP) exert important effects on β-cells to stimulate glucose-dependent
insulin secretion. Both peptides also regulate β-cell proliferation and ... Cited by 283 - Related articles - All 13 versions
AM Lambeir, C Durinx, S Scharpé, I De … - Critical reviews in clinical laboratory sciences, 2003 - informahealthcare.com Laboratory of Medical Biochemistry, University of Antwerp, Universiteitsplein 1,
Wilrijk, Belgium ... Referee: Dr. Albert Adam, Faculté de Pharmace,
Université de Montréal, 2900 Blvd. Edouard—Montpetit, CP succursale ... Cited by 166 - Related articles - BL Direct - All 9 versions
- ►diabetesjournals.org JA Pospisilik, J Martin, T Doty, JA Ehses, N … - Diabetes, 2003 - Am Diabetes Assoc Recent studies into the physiology of the incretins glucose-dependent
insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) have added
stimulation of β-cell growth, differentiation, and cell survival to well- ... Cited by 161 - Related articles - BL Direct - All 4 versions
- ►diabetesjournals.org CF Deacon - Diabetes, 2004 - Am Diabetes Assoc Glucagon-like peptide (GLP)-1 is an incretin hormone with potent
glucose-dependent insulinotropic and glucagonostatic actions, trophic effects on
the pancreatic β-cells, and inhibitory effects on gastrointestinal ... Cited by 154 - Related articles - BL Direct - All 5 versions
- ►diabetesjournals.org J Mu, J Woods, YP Zhou, RS Roy, Z Li, E … - Diabetes, 2006 - Am Diabetes Assoc Inhibitors of dipeptidyl peptidase-4 (DPP-4), a key regulator of the actions of
incretin hormones, exert antihyperglycemic effects in type 2 diabetic patients.
A major unanswered question concerns the potential ability of DPP-4 ... Cited by 126 - Related articles - BL Direct - All 9 versions
DJ Drucker - eid, 2003 - informahealthcare.com Incretins are peptide hormones, exemplified by glucose-dependent insulino-
tropic peptide and glucagon-like peptide 1 that are released from the gut in
response to nutrient ingestion and enhance glucose-stimulated insulin ... Cited by 118 - Related articles - All 6 versions
CF Deacon, B Ahrén, JJ Holst - eid, 2004 - informahealthcare.com Inhibitors of the enzyme dipeptidyl peptidase IV (DPP IV) are of increasing
interest to both diabetologists and the pharmaceutical industry alike, as they
may become established as the next member of the oral antidiabetic class of ... Cited by 102 - Related articles - All 7 versions
- ►diabetesjournals.org JA Pospisilik, SG Stafford, HU Demuth, CHS … - Diabetes, 2002 - Am Diabetes Assoc Upon release into circulation, the potent insulin secretagogues
glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1
(GLP-1) are rapidly cleaved and inactivated by the enzyme dipeptidyl ... Cited by 99 - Related articles - BL Direct - All 6 versions
- ►activx.com [PDF] JS Rosenblum, JW Kozarich - Current opinion in chemical biology, 2003 - Elsevier Much attention has recently been given to a class of proteases that cleave
proteins and peptides after proline residues. This class includes dipeptidyl
peptidase IV (DPP IV; also termed CD26), fibroblast activation protein α ... Cited by 94 - Related articles - All 5 versions
- ►bcell.org [PDF] PE MacDonald, W El-kholy, MJ Riedel, AMF … - Diabetes, 2002 - Am Diabetes Assoc The physiological effects of glucagon-like peptide-1 (GLP-1) are of immense
interest because of the potential clinical relevance of this peptide. Produced
in intestinal L-cells through posttranslational processing of the ... Cited by 95 - Related articles - BL Direct - All 4 versions