- ►physiology.org LL Atkinson, R Kozak, SE Kelly, A Onay- … - American Journal of …, 2003 - Am Physiological Soc The accumulation of intracellular triacylglycerol (TG) is highly correlated with muscle insulin
resistance. However, it is controversial whether the accumulation of TG is the result of increased
fatty acid supply, decreased fatty acid oxidation, or both. Because abnormal fatty acid ... Cited by 38 - Related articles - BL Direct - All 4 versions
- ►endojournals.org T Deng, S Shan, PP Li, ZF Shen, XP Lu, J Cheng, ZQ … - Endocrinology, 2006 - Endocrine Soc Both peroxisome proliferator-activated receptor (PPAR)- and hormone-sensitive lipase
(HSL) play important roles in lipid metabolism and insulin sensitivity. We demonstrate that expression
of the HSL gene is up-regulated by PPAR and PPAR agonists (rosiglitazone and ... Cited by 28 - Related articles - BL Direct - All 7 versions
- ►ub.es [PDF] E Carrasco-Chaumel, J Roselló-Catafau, R Bartrons, R … - Journal of hepatology, 2005 - Elsevier Preconditioning or AMPK activation with aminoimidazole-4-carboxamide ribonucleoside
(AICAR) increased AMPK and constitutive NOS activities and protected against lipid
peroxidation, nitrotyrosine formation and hepatic injury in both grafts. Inhibition of AMPK ... Cited by 21 - Related articles - All 10 versions
JC Clapham - Current Drug Targets, 2004 - ingentaconnect.com Abstract: The pharmacological treatment options for obesity are currently very limited but the
prevalence of the disease is increasing rapidly. Obesity has many serious sequelae, the most
common of which is type-2-diabetes. The benefits of weight loss on health are ... Cited by 15 - Related articles - BL Direct - All 2 versions
- ►queensu.ca [PDF] GB McClelland, CS Kraft, D Michaud, JC Russell, … - BBA-Molecular Basis of …, 2004 - Elsevier Leptin plays a central role in the regulation of fatty acid homeostasis, promoting lipid storage
in adipose tissue and fatty acid oxidation in peripheral tissues. Loss of leptin signaling leads
to accumulation of lipids in muscle and loss of insulin sensitivity secondary to obesity. In ... Cited by 14 - Related articles - All 6 versions
IB Mosbah, J Roselló-Catafau, R Franco-Gou, … - Liver …, 2006 - igl-transplantation.org 8 Ob) were preserved in IGL-1 plus N -nitro-L-arginine methyl ester hydrochloride (L-NAME).
Hepatic injury and function (aminotransferases, bile production, bromosulfophthalein
clearance), and factors potentially involved in the susceptibility of steatotic livers to ... Cited by 13 - Related articles - View as HTML - BL Direct - All 6 versions
IB Mosbah, M Massip-Salcedo, I Fernández-Monteiro, … - Liver Transplantation, 2007 - ub.es This study investigates how the addition of trimetazidine (TMZ) and aminoimidazole-4-carboxamide
ribonucleoside (AICAR) to University of Wisconsin (UW) solution protects steatotic livers. Steatotic
and nonsteatotic livers were preserved for 24 hours at 4°C in UW and UW with TMZ and ... Cited by 7 - Related articles - View as HTML - BL Direct - All 3 versions
- ►physiology.org JC Russell, SD Proctor, SE Kelly, DN … - American Journal of …, 2008 - Am Physiological Soc Rats of the JCR:LA-cp strain, which are homozygous for the cp gene (cp/cp), are obese,
insulin-resistant, and hyperinsulinemic. They exhibit associated micro- and macrovascular disease
and end-stage ischemic myocardial lesions and are highly stress sensitive. We subjected ... Cited by 1 - Related articles - All 4 versions