- ►diabetesjournals.org L Quagliaro, L Piconi, R Assaloni, L Martinelli, … - Diabetes, 2003 - Am Diabetes Assoc The effects of intermittent and constant high glucose in the formation of
nitrotyrosine and 8-hydroxydeoxyguanosine (markers of oxidative stress), as well
as the possible linkage between oxidative stress and apoptosis in ... Cited by 193 - Related articles - BL Direct - All 4 versions
- ►asnjournals.org T Inoguchi, T Sonta, H Tsubouchi, T Etoh, M … - Journal of the American Society of Nephrology, 2003 - Am Soc Nephrol Hyperglycemia seems to be an important causative factor in the development of
micro- and macrovascular complications in patients with diabetes (1,2). Various
pathophysiological and biochemical mechanisms have been proposed to explain ... Cited by 126 - Related articles - BL Direct - All 5 versions
- ►alfediam.org [PDF] B Fromenty, MA Robin, A Igoudjil, A Mansouri … - Diabetes and Metabolism, 2004 - Elsevier Rich diet and lack of exercise are causing a surge in obesity, insulin
resistance and steatosis, which can evolve into steatohepatitis. Steatosis and
nonalcoholic steatohepatitis (NASH) can also be induced by drugs such as ... Cited by 105 - Related articles - BL Direct - All 4 versions
T Sonta, T Inoguchi, H Tsubouchi, N … - Free Radical Biology and Medicine, 2004 - Elsevier It is well established that oxidative stress is enhanced in diabetes. However,
the major in vivo source of oxidative stress is not clear. Here we show that
vascular NAD(P)H oxidase may be a major source of oxidative stress in ... Cited by 85 - Related articles - All 5 versions
T Etoh, T Inoguchi, M Kakimoto, N Sonoda, K … - Diabetologia, 2003 - Springer Aim/hypothesis. An increased production of reactive oxygen species (ROS) could
contribute to the devel- opment of diabetic nephropathy. NAD(P)H oxidase might
be an important source of ROS production in kidney as reported in blood ... Cited by 79 - Related articles - BL Direct - All 3 versions
ML Caramori, M Mauer - Current opinion in nephrology and hypertension, 2003 - journals.lww.com Recent findings: There have been advances in the understanding of diabetic
nephropathy pathology. Clearly, structural changes may be advanced before any
clinical findings are apparent. Not all functional consequences of the ... Cited by 68 - Related articles - BL Direct - All 7 versions
- ►diabetesjournals.org FR DeRubertis, PA Craven, MF Melhem, EM … - Diabetes, 2004 - Am Diabetes Assoc The effects of overexpression of Cu 2+ /Zn 2+ superoxide dismutase-1 (SOD-1) on
indexes of renal injury were compared in 5-month-old nontransgenic (NTg) db/db
mice and db/db mice hemizygous for the human SOD-1 transgene (SOD-Tg). Both ... Cited by 59 - Related articles - BL Direct - All 4 versions
JA Scott, GL King - Ann NY Acad Sci, 2004 - interscience.wiley.com Abstract: The many studies on oxidative stress, antioxidant treatment, and
diabetic complications have shown that oxidative stress is increased and may
accelerate the development of complications through the metabolism of ... Cited by 53 - Related articles - All 6 versions
IG Obrosova, L Fathallah, E Liu, J Nourooz- … - Free Radical Biology and Medicine, 2003 - Elsevier Oxidative stress is implicated in the pathogenesis of diabetic nephropathy. The
attempts to identify early markers of diabetes-induced renal oxidative injury
resulted in contradictory findings. We characterized early oxidative stress ... Cited by 54 - Related articles - All 4 versions
T Kuroki, K Isshiki, GL King - Journal of the American Society of Nephrology, 2003 - Am Soc Nephrol Oxidative stress is increased in both diabetic and insulin resistance states and
may contribute to the development of microvascular and cardiovascular diseases
associated with both of these syndromes (1–4). In addition, oxidative ... Cited by 43 - Related articles - BL Direct - All 5 versions
