LM Maier, JMM Howson, N Walker, GP Spickett, … - The Journal of Allergy and …, 2006 - Elsevier Using the largest sample sizes reported so far for the identification of genetic determinants of
circulating IgE levels, we investigated associations between total serum IgE
(log-transformed) and single nucleotide polymorphisms in 8 genes that are candidate ... Cited by 25 - Related articles - All 36 versions
L Windsor, G Morahan, D Huang, V McCann, T Jones, I … - Human immunology, 2004 - Elsevier Carriage of a polymorphism in the 3′untranslated region of the IL12B gene encoding IL-12p40
was investigated in subjects with type 1 diabetes mellitus stratified by age at diagnosis (n =
648) and compared with a population-based control cohort (n = 246) residing in Western ... Cited by 23 - Related articles - All 3 versions
- ►bmj.com R Bergholdt, P Ghandil, J Johannesen, OP … - British Medical …, 2004 - jmg.bmj.com Confirmation of the significance of the IL12B 3'UTR polymorphism in T1DM in other populations
is important. The aims of our study were to seek confirmation of the involvement of the IL12B
C1159A SNP in T1DM susceptibility in a population based Danish family collection of 337 ... Cited by 22 - Related articles - All 5 versions
- ►oxfordjournals.org E Sanchez, S Morales, L Paco, MA Lopez-Nevot, … - …, 2005 - Br Soc Rheumatology Instituto de Parasitología y Biomedicina López-Neyra, CSIC, 1 Servicio de Inmunología and
2 Servicio de Medicina Interna, Hospital Virgen de las Nieves, Granada, 3 Servicio de
Inmunología, Hospital Virgen del Rocío, Seville, 4 Servicio de Reumatología, Hospital ... Cited by 15 - Related articles - BL Direct - All 4 versions
G Orozco, MA González-Gay, L Paco, MA López-Nevot, … - Human Immunology, 2005 - Elsevier The aim of this study was to assess the possible association between the IL12B and the IL12RB1
gene polymorphisms and the systemic autoimmune disease rheumatoid arthritis (RA). Our study
population consisted of 545 patients with RA and 393 healthy subjects. All the individuals ... Cited by 11 - Related articles - All 2 versions
JM Yang, S Nagasaka, T Yatagai, T Nakamura, I … - Diabetes research and …, 2006 - Elsevier The present study was undertaken to clarify a role of interleukin-12p40 gene (IL-12B)
polymorphism, located on chromosome 5q33-34 (IDDM 18), in Japanese subjects with Type
1 diabetes mellitus (T1DM) and autoimmune thyroid diseases (AITD). In 179 subjects with ... Cited by 4 - Related articles - All 9 versions
P Holm, H Luthman, I Kockum - ANNALS-NEW YORK …, 2003 - interscience.wiley.com Abstract: Type 1 diabetes mellitus (T1DM) is an autoimmune disease in which the β cells in the
pancreas are destroyed by the body's own immune system. IL12 plays a role in pathological
situations, such as septic shock, tissue damage during inflammation, and organ-specific ... Cited by 4 - Related articles - BL Direct - All 5 versions
YS Wei, Y Lan, B Luo, D Lu, HB … - Mol Carcinog [Epub ahead …, 2009 - interscience.wiley.com Nasopharyngeal carcinoma (NPC) is multifactorial, and the genetic background may be a crucial
etiologic factor. Interleukin-12 (IL-12) is a multifunctional cytokine that induces interferon
(IFN)-gamma secretion and plays an important role in antitumor immunity. Interleukin-27 ... Cited by 2 - Related articles - All 2 versions
AD Paterson - Current Diabetes Reports, 2006 - Springer The evidence that there is clinical heterogeneity of type 1 diabetes is reviewed and the implications
for genetic studies are discussed. In the past year, genome-wide linkage analysis of 1435 multiplex
families was reported. Additionally, confirmed evidence for association of spe- cific ... Cited by 2 - Related articles - BL Direct - All 3 versions
