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Scholar Results 1 - 10 of about 62 citing Matsumoto: Role of the insulin receptor substrate 1 and phosphatidylinositol 3-kinase signaling.... (0.13 sec) 

Diabetic dyslipidaemia: from basic research to clinical practice*


MR Taskinen - Diabetologia, 2003 - Springer
The recognition that the increase of plasma triglyce- ride rich lipoproteins
(TRLs) is associated with multi- ple alterations of other lipoproteins species
that are potentially atherogenic has expanded the picture of diabetic ...
Cited by 246 - Related articles - BL Direct - All 7 versions

[PDF] New perspectives in the regulation of hepatic glycolytic and lipogenic genes by insulin and …


F Foufelle, P Ferré - BIOCHEMICAL JOURNAL-LONDON-, 2002 - bj.portlandpress.com
The regulation of hepatic glucose metabolism has a key role in whole-body energy
metabolism, since the liver is able to store (glycogen synthesis, lipogenesis)
and to produce (glycogenolysis, gluconeogenesis) glucose. These pathways ...
Cited by 219 - Related articles - View as HTML - BL Direct - All 9 versions

Impaired IRS-1/PI 3-kinase signaling in patients with HCV: A mechanism for increased …


S Aytug, D Reich, LE Sapiro, D Bernstein, N … - Hepatology, 2003 - interscience.wiley.com
Patients with hepatitis C virus (HCV) infection have a greater risk of
developing type 2 diabetes mellitus. However, the mechanism of this association
is unclear. In this study, we examined the potential defects in upstream ...
Cited by 119 - Related articles - All 4 versions

Lipoprotein lipase: the regulation of tissue specific expression and its role in lipid and …


K Preiss-Landl, R Zimmermann, G Hämmerle, … - Current opinion in lipidology, 2002 - journals.lww.com
Purpose of review The aim of this review is to summarize and discuss recent
advances in the understanding of the physiological role of lipoprotein lipase in
lipid and energy metabolism. Recent findings Studies on the transcriptional ...
Cited by 117 - Related articles - BL Direct - All 7 versions

Role of STAT-3 in regulation of hepatic gluconeogenic genes and carbohydrate metabolism …


H Inoue, W Ogawa, M Ozaki, S Haga, M … - Nature medicine, 2004 - nature.com
Cited by 101 - Related articles - BL Direct - All 5 versions

Complementary roles of IRS-1 and IRS-2 in the hepatic regulation of metabolism

- nih.gov
CM Taniguchi, K Ueki, CR Kahn - Journal of Clinical Investigation, 2005 - Am Soc Clin Investig
Hepatic insulin resistance is a critical component in the development of type 2
diabetes mellitus. In many cases, insulin resistance in liver is associated with
reduced expression of both major insulin receptor substrate (IRS) proteins, ...
Cited by 88 - Related articles - All 10 versions

PKCλ in liver mediates insulin-induced SREBP-1c expression and determines both hepatic …

- nih.gov
M Matsumoto, W Ogawa, K Akimoto, H Inoue, … - Journal of Clinical Investigation, 2003 - Am Soc Clin Investig
PKCλ is implicated as a downstream effector of PI3K in insulin action. We show
here that mice that lack PKCλ specifically in the liver (L-λKO mice), produced
with the use of the Cre-loxP system, exhibit increased insulin sensitivity ...
Cited by 74 - Related articles - BL Direct - All 11 versions

Regional differences of insulin action in adipose tissue: insights from in vivo and in vitro …


F Giorgino, L Laviola, JW Eriksson - Acta Physiologica Scandinavica, 2005 - interscience.wiley.com
Adipose tissue is now recognized to have a multitude of functions that are of
importance in the regulation of energy balance and substrate metabolism.
Different hormones, in particular insulin and catecholamines, govern the ...
Cited by 73 - Related articles - All 8 versions

Antisense oligonucleotide reduction of DGAT2 expression improves hepatic steatosis and …


XX Yu, SF Murray, SK Pandey, SL Booten, D … - Hepatology, 2005 - interscience.wiley.com
In this study, we investigated the role of acyl-coenzyme A:diacylglycerol
acyltransferase 2 (DGAT2) in glucose and lipid metabolism in obese mice by
reducing its expression in liver and fat with an optimized antisense ...
Cited by 72 - Related articles - BL Direct - All 3 versions

The combination of SOX5, SOX6, and SOX9 (the SOX trio) provides signals sufficient for …


T Ikeda, S Kamekura, A Mabuchi, I Kou, S … - Arthritis Care & Research - interscience.wiley.com
It is also possible that your web browser is not configured or not able to
display style sheets. In this case, although the visual presentation will be
degraded, the site should continue to be functional. We recommend using the ...
Cited by 64 - Related articles - BL Direct - All 3 versions


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